Cachexia

Introduction The term cachexia comes from the Greek words "kakos" and "hexis", which literally mean "bad conditions." It can occur in a variety of diseases, including tumors, AIDS, severe trauma, post-operative, malabsorption and severe sepsis. Among them, the cachexia associated with tumors is the most common, called tumor cachexia. It is a tumor that changes the metabolism of the body through various ways, so that the body can not absorb nutrients from the outside. The tumor builds itself from the body's inherent fat and protein, so the body loses a lot of nutrients, especially essential amino acids and vitamins. Formed by decomposition of fatty proteins). The oxidation process in the body is weakened, the oxidized incomplete products are accumulated, and the nutrients cannot be fully utilized, resulting in a waste-based metabolism-based state, insufficient calories, which in turn causes loss of appetite, can only enter a small amount of diet or can not eat at all, extremely thin, skinny Only the bone shelf is left, like a sputum, anemia, weakness, complete bed rest, life can not take care of themselves, extreme pain, systemic failure and other syndromes. Medically refers to the phenomenon of systemic functional decline such as significant weight loss, anemia, and mental dysfunction in the human body. It is caused by cancer and other serious chronic diseases. The occurrence of this syndrome refers to the state of severe dysfunction. Also known as cacao. This name is derived from the concept of humoral pathology. Humoral pathology believes that the essence of the disease lies in the abnormality of body fluids. The original text is from Hippocrates and Gale-nos. It now refers to the state of systemic failure that occurs in advanced stages of cancer, tuberculosis, and hemophilia. It can be seen as a poisoning state caused by many organs in the body. The symptoms are weight loss, anemia, fatigue, and the skin is stained yellow.

Cause

It is a tumor that changes the metabolism of the body through various ways, so that the body can not absorb nutrients from the outside. The tumor builds itself from the body's inherent fat and protein, so the body loses a lot of nutrients, especially essential amino acids and vitamins. Formed by decomposition of fatty proteins). The oxidation process in the body is weakened, the oxidized incomplete products are accumulated, and the nutrients cannot be fully utilized, resulting in a waste-based metabolism-based state, insufficient calories, which in turn causes loss of appetite, can only enter a small amount of diet or can not eat at all, extremely thin, skinny Only the bone shelf is left, like a sputum, anemia, weakness, complete bed rest, life can not take care of themselves, extreme pain, systemic failure and other syndromes.

an examination

Related inspection

Blood routine tumor associated antigen

(1) Physical nutritional status check: Progressive weight loss in March, body weight decreased by 7.5% compared with the original body weight (diagnosis), or IBM index <80%.

(2) Medical history data: accompanied by loss of appetite (poor appetite, food consumption is reduced by 1/3 than when healthy), fatigue.

(3) Blood test: total protein <55g/l, albumin <35g/l, prealbumin <250mg/l.

Differential diagnosis

It is necessary to distinguish from diabetes, hyperthyroidism and other diseases due to hormone secretion leading to weight loss, which is caused by various tumors.

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