Thinning of the gallbladder wall

Introduction Papillary adenocarcinoma may be caused by malignant papillary or polyps. The tumor grows into the gallbladder cavity, affecting the emptying of the gallbladder, and there are ulcers on the surface of the tumor, which may cause infection. If the tumor blocks the gallbladder neck, it can enlarge the gallbladder and thin the gallbladder wall, similar to gallbladder abscess or effusion. The cells hyperplasia, forming a single or dendritic nipple that protrudes into the sac. The cytoplasm of cancer cells is slightly basophilic, with large nucleus, different morphology, deep staining, and more mitotic division. There are a small amount of fibrous tissue interstitial between cancer cells or nipples, often with inflammatory cell infiltration, but no lymphoid tissue. .

Cause

(1) General form

The tumor looks like a mixed tumor, which is round or nodular, and has no membrane. Tumors are common in the cystic cavity, and the inner wall of the cavity is not smooth, and may have some papillae or granular.

(two) microscopic examination

Cancer cells vary in size and are columnar or cuboidal, and form a variety of irregular adenoid structures, many of which are significantly enlarged to form a sac. The cells are arranged in a disordered manner, although they are arranged in a single layer or a plurality of layers, and the cancer cells are extremely proliferated, forming a single or dendritic nipple that protrudes into the cystic cavity. The cytoplasm of cancer cells is slightly basophilic, with large nucleus, different morphology, deep staining, and more mitotic division. There are a small amount of fibrous tissue interstitial between cancer cells or nipples, often with inflammatory cell infiltration, but no lymphoid tissue. . The tumor capsule is incomplete and sometimes the tumor cells invade into or around the tissue.

(3) Biological characteristics

Papillary cystadenocarcinoma grows in different speeds, can follow the blood, lymphatic metastasis, and can also invade the nerves.

an examination

Related inspection

Intravenous cholangiography oral cholangiography liver, gallbladder, spleen CT cholangiography

Tumor-like malignant mixed tumors, the common symptoms are a local painless mass, which grows faster, and some are longer and have nodular shape. Since the glandular cavity is enlarged to form a saclike shape, and hemorrhage and necrosis can occur, cystic changes often occur. The palpation part is soft, and the puncture can draw hemorrhagic secretions. Generally no obvious adhesions and activities in the early stage. As the tumor grows, the activity gradually worsens, and it adheres to the surrounding tissues and easily invades the deep adjacent tissues, including the chewing muscles and the mandible.

Differential diagnosis

To identify whether the tumor is benign or malignant, and to identify whether it is from the parotid gland or the submandibular gland.

Papillary cystadenocarcinoma is most common in the parotid gland, followed by the parotid parotid gland and submandibular gland, and small parotid glands in the buccal mucosa, the base of the mouth, the tongue and the upper lip can also occur. According to Dong Shaozhong's report, the age of onset is 12 to 72 years old, with an average of 42.5 years old. It is more common in 30 to 50 years old, and the ratio of male to female is 2:1.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.