Intestinal stasis

Introduction The blind sputum syndrome (enteric bacterial overgrowth syndrome (EBOS), mainly due to small intestinal stagnation, bacteria in the small intestine overgrowth and cause malabsorption, also known as intestinal collapse syndrome, intestinal infection syndrome or blind sputum syndrome . Overgrowth of intestinal bacteria can directly or indirectly affect the structure and function of the intestine, causing malabsorption. When the intestinal bacteria grows excessively, the bacteria can compete with the host for vitamin B12 in the diet. Although internal factors can inhibit the competition of vitamin B12 by aerobic bacteria, their rate of vitamin B12 intake is slowed down, but intestinal deposition can provide time for their intake.

Cause

Causes

Under normal circumstances, the stomach and upper small intestine contain only a small amount of bacteria, because gastric acid and small intestine advancement can inhibit and eliminate bacteria. Any cause of hypoacidity or slowing or disruption of bowel movements can lead to excessive bacterial growth in the small intestine.

Bacterial hyperplasia in the stomach

Low acid or no acid, gastric mucosal atrophy, postoperative gastric movement or abnormal anatomy (such as residual stomach after partial gastrectomy) have almost no gastric fundus glandular cells and no acid. In addition, Sachs studies have demonstrated that omeprazole inhibits H-K-ATPase in parietal cells and inactivates them. The binding of this proton pump inhibitor to the enzyme is irreversible, until the new enzyme in the cell is synthesized and transported to the apical membrane, and the enzyme activity is restored. This update process takes 48 hours, so taking 1 omeprazole can continue. 48h low acid.

2. Small intestinal deposition

(1) Anatomical reasons: input sputum of Billroth II surgery or gastrectomy, duodenal jejunal diverticulum, blind sputum caused by surgery, recurrent sputum surgery, intestinal stenosis, adhesions, inflammation and lymphoma obstruction.

(2) intestinal dyskinesia: scleroderma, idiopathic small intestine pseudo-obstruction, transitional complex motor absence or disorder, diabetic autonomic neuropathy.

(3) Abnormal intestinal passage: gastric-colon or jejunum-colon fistula, ileocecal valve resection.

3. Other

Chronic pancreatitis, immunodeficiency syndrome.

an examination

Related inspection

Ultrasound examination of gastrointestinal diseases, gastrointestinal imaging, gastrointestinal CT examination

X-ray gastrointestinal angiography showed anatomical or functional abnormalities such as diverticulum, blind sputum, and fistula. Fibrocolonoscopy and biopsy can help with the diagnosis of the cause.

Differential diagnosis

Differential diagnosis

Any slow-onset diarrhea, steatorrhea, weight loss, large cell anemia, especially in the elderly or patients with a history of abdominal surgery should consider intestinal bacterial overgrowth in the differential diagnosis.

1. A dysbacteriosis caused by antibiotics.

2. Gastrin (gastrin) deficiency after gastric antrum resection.

3. Intra-factor deficiency after subtotal or total gastrectomy.

4. Short bowel syndrome.

5. Primary intestinal malabsorption syndrome.

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