Super male

Introduction Superman's syndrome, also known as XYY chromosome syndrome, is a patient with a chromosome of 47XYY, first discovered in 1961. In their sexual chromatin, X-chromatin was negative and Y-chromatin double-positive. The karyotype is 47,XYY, and the extra Y chromosome is due to the fact that the chromosomes of the father's germ cells are not separated. According to the statistical performance (a series of reports in foreign countries), the criminal crime rate of patients with XYY syndrome is higher than that of the normal population, which is about several to ten times. It is worthy of people's attention that another chromosomal abnormality in 47,XXY patients, the crime rate has also increased, similar to the karyotype of 47,XYY. This explains from the opposite side that more than one Y chromosome is not the determining factor, and the decisive role should be the intelligent low and central nervous system abnormalities.

Cause

Because they are male, but have a chromosome associated with men, they are too masculine. Karyotype analysis found that there is a Y chromosome more than normal males. The excess Y-staining system is caused by the separation of chromosomes in the process of spermatogenesis, that is, the sperm cells do not separate during mitosis, forming XYY spermatogonia or may be in the reduction The Y chromosome does not separate during the separation phase. The fertility of patients varies greatly, and may be infertile or partially fertile.

an examination

Related inspection

Karyotype analysis

The body is up to 1.8 meters (European and American average of 1.85 meters), the trunk and leg length are increased, the muscle tension is low, and the movement is uncoordinated. The face is asymmetrical and the ears are long. Often suffering from pustular acne. Medically, these people are called "super men", but in fact 15-20% of patients have moderate hypogonadism, and spermatogenesis is normal to mildly damaged. Clinical examination results of less refined patients showed abnormal spermatogenesis. They can have normal or abnormal offspring or no offspring. Its HY antigen titer is higher than normal males.

Smart low or at the lower limit of normal. The patient lacks self-control and has poor emotional control. Some foreign scholars believe that patients have violent temper, aggressive, aggressive, anti-social behavior, easy to commit crimes, including crimes of improper sexual behavior. Gas brain angiography can have brain atrophy, and the slow alpha frequency in the EEG increases, which is consistent with the central nervous system defects. The cause of the crime is not related to the tall body and hypogonadism, but to the lack of intelligence and central nervous system abnormalities. The discovery of this chromosomal abnormality is considered to be an important discovery of human behavioral genetics. However, this issue is still a matter of debate in behavioral genetics and needs to be discussed.

According to the statistical performance (a series of reports in foreign countries), the criminal crime rate of patients with XYY syndrome is higher than that of the normal population, which is about several to ten times. It is worthy of people's attention that another chromosomal abnormality in 47,XXY patients, the crime rate has also increased, similar to the karyotype of 47,XYY. This explains from the opposite side that more than one Y chromosome is not the determining factor, and the decisive role should be the intelligent low and central nervous system abnormalities.

Differential diagnosis

The differential diagnosis of super male:

1 Male with 1 X chromosome: also known as congenital testicular hypoplasia syndrome, the incidence rate is about 1 / 1000, its chromosome composition is 47, that is, 47,XXY. Clinically, the testicular and male sexual dysplasia is the main feature, which is called euro-like body posture. It is characterized by delicate skin, thin hair, no beard, mane and pubic hair. The testicles are as large as broad beans, peanuts or soybeans. The penis is short, the erection is not or not strong, the tone is sharp, the larynx is flat, and the breast is mildly developed. Generally, the body is tall, and the body is mostly obese. When walking, the body sways in the same direction as the "penguin-like" gait. No fertility, semen check for inactive sperm. Some patients have lower mental development than normal, showing mild mental retardation. Psychological personality development is characterized by immatureness and passiveness, manifested as emotional indifference, calmness, timidity, clumsy movements, indecisiveness, less friends, lack of self-motivation and strength. I am often uneasy about my lack of masculinity. I am very anxious about sexual dysfunction and lack of fertility. They form greater psychological pressure. Sometimes sexual crimes or other anti-social behaviors may occur, and some mental and psychological barriers may occur.

2 Males have more than one Y chromosome: also known as super male syndrome, the incidence rate is about 1 / 1500, the chromosome composition is also 47, that is, 47,XYY. In clinical practice, it is characterized by a tall body, often up to 190 cm or more, often accompanied by facial shape specific or mild asymmetry of the body, facial acne, some patients may have sports disharmony or tremor, etc., and no more The shape of the body is abnormal. Although its intelligent development is in the normal range, it is mostly at the lower middle level. Personality development has deviated from normal since childhood. It is characterized by instability and susceptibility to outbreaks. Personality is brutal, lack of patience, can not withstand setbacks, irritability, and even some impulsive violence. It is prone to social maladjustment or mental disorders.

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