Extreme weakness after childbirth

Introduction Psilotype anterior hypofunction (also known as "Schiehan's disease") is caused by multiple lesions of the pituitary or hypothalamus involving the endocrine function of the pituitary. The disease is more common in women, and is associated with pituitary avascular necrosis caused by postpartum hemorrhage. The main symptom is extreme weakness after childbirth.

Cause

1. Avascular necrosis of the anterior pituitary: the postpartum pituitary necrosis is called Sheehan syndrome. Pituitary ischemic infarction can also occur in diabetic microangiopathy.

2. Pituitary and hypothalamic tumors.

3. Pituitary invasive disease: leukemia, sarcoidosis, etc.

4. Autoimmune pituitary inflammation.

5. Others: radiotherapy and chemotherapy; pituitary resection; pituitary abscess, tuberculosis, encephalitis, skull base meningitis and other infectious diseases; empty sella syndrome (rare).

6. Idiopathic: mostly a single hormone deficiency.

an examination

Related inspection

Glucose growth hormone

symptom:

1. There are primary causes of infection: such as postpartum hemorrhage, pituitary tumors, pituitary surgery or radiation therapy, craniocerebral trauma, infection or inflammation (tuberculosis, syphilis, meningoencephalitis), systemic diseases (leukemia, lymphoma, cerebral artery Hardening, malnutrition) and immune pituitary inflammation.

2. Gonadotropin and prolactin secretion deficiency group: postpartum no milk, amenorrhea, yin, sputum, eyebrows shedding, sparse (male beard scarce), loss of libido, disappearance, external genital atrophy, uterus, breast atrophy (male impotence , testicles, prostate atrophy).

3. Thyroid-stimulating hormone deficiency group: less gas lazy words, apathy, mental retardation, slow movement, loss of appetite, chills, less sweat, dry skin, facial swelling, yellow, and even mucous edema.

4. Adrenocortical hormone deficiency group: dizziness, weakness, nausea, vomiting, abdominal pain, diarrhea, weight loss, blood pressure drop, easy infection and syncope, even shock, coma.

5. Pituitary crisis: If there are various kinds of stress, infection, surgery, trauma, mental stimulation, digestive tract diseases, certain drugs (sedation, anesthetics and hypoglycemic drugs, etc.) can aggravate the primary disease and induce crisis occur.

an examination:

1. Hypoglycemia, a low glucose tolerance curve, or a reactive hypoglycemia curve, which is abnormally sensitive to insulin.

2. Plasma anterior pituitary hormones such as growth hormone (GH), prolactin (PRL), thyroid stimulating hormone (TSH), adrenocorticotropic hormone (ACTH), follicle stimulating hormone (FSH), luteinizing hormone (LH) The average is low. The pituitary gland does not respond to the stimulation of the hypothalamic release hormone (such as TRH, LHRH stimulation test) or the reaction is mild.

3. Secondary gonad, thyroid, adrenal insufficiency. Serum testosterone, estradiol, thyroid hormone, cortisol levels are reduced, but delayed response to the corresponding exogenous pituitary stimulating hormone (such as the ACTH stimulation test).

Differential diagnosis

It should be differentiated from anorexia nervosa and target gland function. Long-term primary hypothyroidism can also cause TSH cell proliferation and pituitary enlargement, and do not mistake pituitary hypofunction caused by pituitary tumors.

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