Middle ear and eustachian tube ciliary abnormalities

Introduction Ciliary structural defects and clearing dysfunction can lead to abnormalities in the middle ear and eustachian tube cilia, which can cause chronic recurrent otitis media, tympanic membrane perforation, and ear pus. The disease is autosomal recessive. It has been confirmed that the cilia axis filament contains more than 100 polypeptide health searches, and any one of the polypeptide defects can cause the same pathological result, and thus has obvious genetic heterogeneity. Abnormalities in the middle ear and eustachian tube cilia, which are usually caused by infection and inflammation caused by cilia abnormalities, can cause discomfort to the patient, such as pain, itching, cough and so on.

Cause

The disease is autosomal recessive. It has been confirmed that the cilia axis filament contains more than 100 polypeptide health searches, and any one of the polypeptide defects can cause the same pathological result, and thus has obvious genetic heterogeneity. Ciliary structural defects and clearing dysfunction can lead to abnormalities in the middle ear and eustachian tube cilia, which can cause chronic recurrent otitis media, tympanic membrane perforation, and ear pus. Can cause discomfort to the patient, such as pain, itching, coughing, etc.

an examination

Related inspection

Middle ear ear examination otoscopy

The diagnosis can be confirmed according to the patient's clinical manifestations and mucosal biopsy. The middle ear is a gas-filled irregular cavity, mostly located in the tibial rock. The middle ear is separated from the external auditory canal by the tympanic membrane, and is adjacent to the inner ear canal inward, and leads to the nasopharynx by the eustachian tube. Through otoscopy, hearing examination, X-ray examination to check whether there is otitis media.

Otoscopy: The middle ear mucosa can also be observed through the tympanic membrane hole. Chronic granulomatous tympanitis on the tympanic membrane, whether the external auditory canal is narrow or curved, should also be observed. If you can notice the above points during otoscopy, it will be very helpful for treatment.

Hearing test: Early or several cases with conductive hearing impairment, severe or long-term cases, there are mild to severe mixed hearing impairment, and more serious may also be full.

X-ray examination: Most chronic otitis media is a sequela of repeated otitis media in children, so most of the mastoid gasification is poor. A small number of mastoid gasification is good, mostly tympanic membrane long-term cavernous otitis media, or chronic otitis media caused by trauma and talent.

Differential diagnosis

Diagnosis: Can be diagnosed based on the patient's clinical presentation and mucosal biopsy.

Identification: bacteria into the drumstick caused by purulent infection, known as acute suppurative otitis media, and more secondary to upper respiratory tract infection, may be part of the case from the beginning of the virus infection, and then bacterial invasion. Commonly, it is hemolytic streptococcus, Staphylococcus aureus, type III pneumococci and proteus. More common in winter and spring, blood diseases, malnutrition, allergy and cardiopulmonary patients, nephritis, diabetes are easy to induce. According to statistics, the incidence of children aged 5 to 16 years old is as high as 3%, and those under 5 years old are as high as 5% to 10%, and sometimes repeated attacks.

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