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Palmoplantar hyperkeratosis

Introduction
Cause
Examine
Diagnosis

Introduction

Introduction Excessive keratosis refers to local skin keratinization, dry skin, scaly, chapped, generally no subjective discomfort, sometimes itching or pain, often aggravating symptoms in winter. Most of them are infancy, and apical palmoplantar keratosis usually occurs between the ages of 15 and 30. Autosomal dominant hereditary, Melede and Papillon-Lefevre syndromes are recessive. A keratinous thickening plaque with a clear boundary of the lesion, with a yellowish color such as sputum, or a mostly round or oval keratinized papule.

Cause

Cause

Usually a genetic disease.

1, mostly infancy onset, psoriasis keratosis usually occurs between the ages of 15 to 30 years old.

2, autosomal dominant hereditary type, Melede type and Papillon-Lefevre syndrome is a recessive hereditary type.

3, excessive palmar keratosis is diffuse or limited, but also can be linear, point-like.

4. The keratinous thickening plaque with clear boundary of the lesion site, such as yellowish sputum, or most round or oval keratotic papules.

5, often symmetric distribution.

6, Melede type palmar keratosis is often accompanied by palmar sweating, deck thickening, psoriasis-like damage in other parts.

7, Papillon-Lefevre syndrome is often accompanied by hand and foot odor and periodontal disease.

Examine

an examination

Related inspection

Skin color skin elasticity check physical examination of skin diseases

The patient's symptoms can be diagnosed.

Diagnosis

Differential diagnosis

The symptoms of hyperkeratosis of the palmar palsy need to be distinguished from the symptoms below.

Ichthyosis: commonly known as ichthyosis. When the epidermis is increased or the adhesion is increased, scales may be generated, the scales are close to the surface and the edges are free, and the scales are arranged like fish scales, hence the name. According to its different genetic methods, it is divided into ichthyosis vulgaris, X-linked ichthyosis, lamellar ichthyosis and epidermolytic hyperkeratosis. It is the most common form of autosomal dominant ichthyosis, and it is estimated that one out of every 250 people may have this disease. The disease begins in young years and varies in severity. The lighter skin is only dry in winter, with a small amount of powdery scales and hairy moss. Some cases become lighter with age. Scales are usually made with limbs.

In cold and dry climates, the scaly and heel keratosis of the back and calves are more pronounced, and the palms and ankles can be split in a straight line. Sexual ichthyosis is a hereditary recessive hereditary, less common, only found in males, after onset or in infancy. Skin lesions are more common than ichthyosis, large and significant scaly, large yellow-stained or black-stained scaly scales can be spread throughout the body, the abdomen is particularly heavy than the back. Generally, follicular keratinization and palmar keratinization do not occur. With age, skin lesions are not alleviated, but worse. Lamellar ichthyosis is autosomal recessive. Skin lesions appear at birth or shortly after birth. They are characterized by large yellow-gray scales, which are square, with a central sticking, high edges, severe cases like armor, and a slightly flush base. Epidermal loosening hyperkeratosis is an autosomal dominant inheritance, formerly known as bullous ichthyosis-like erythroderma.

At the beginning of the skin, it is red, moist, and painful. After a few days, thick scaly scales form. The scaly patches are polygonal and have deep red cracks around them, which ooze odorous bloody fluids. Hard keratin covers the entire body of the child, affecting breathing and swallowing, and most of them die within a few days after birth. The limited type has thicker squamous keratin slices only on the flexor and wrinkles of the extremities. This type is rare.

Palmoplantar keratosis: a group of hereditary diseases characterized by marked keratinization of the palmar palpebral. Common ones are diffuse and disseminated, all of which are autosomal dominant. Diffuse palmoplantar keratosis is more common in childhood, manifested as obvious pale yellow keratosis, hard and smooth surface. In severe cases, it can proliferate like a scorpion, and there is a split in winter, involving the elbow, knee, ankle and sputum. Lighter can only affect the foot. Disseminated palmoplantar keratosis, also known as punctate palmoplantar keratosis, is characterized by a large round miliary to mung bean keratotic papules, hard and scattered in the palm of the hand.

The more prominent ones in acquired keratosis are ecdysis and menopausal keratoderma.

Fury: A skin manifestation of vitamin A deficiency. When vitamin A is deficient, it may be caused by its ability to inhibit polyamine synthesis, which causes this disorder characterized by hyperkeratosis. Occurs in children and young people, the performance of the upper extremity stretch side, the outer side of the thigh and the trunk, etc. There are many miliary large follicular papules, conical, dark red, hard, central spinous horny plug, remove the angle plug After leaving a small pit. Generally no symptoms. Because of the dense papules, the skin looks like a sable skin, hence the name.

Menopausal keratoderma

Found in menopausal women, the performance of palm, ankle or palm and sputum at the same time hyperkeratosis, there is significant thickening. The disease can also be seen after ovarian or hysterectomy. Treatment with female hormones is ineffective.