Round or oval papules or nodules

Introduction Round or oval rashes or nodules are a symptom that occurs as a result of the formation of cutaneous fibroids.

Cause

Causes of round or oval rash or nodules:

Due to the production of cutaneous fibroids.

an examination

Related inspection

Tumor-associated antigen-associated antigen (Kveim) test

Examination of round or oval rash or nodules:

1. History: Local history of minor trauma or viral infection.

2. Clinical features: intradermal papules or nodular health search, yellow brown or light red and other non-adhesive with deep tissue, "dimple" sign positive.

3. Histopathological examination: consistent with pathological changes of cutaneous fibroma.

Differential diagnosis

Symptoms of round or oval rash or nodules:

Round or oval rash or nodular disease should be differentiated from granulosa cell tumor, disseminated lenticular skin fibrosis, clear cell acanthoma, melanoma, etc.

1. Protuberance cutaneous fibrosarcoma: many cellular components; large nuclear and slightly heteromorphic, more schizophrenia. Progressive enlargement, the diameter of more than 2 ~ 3cm suggests malignant fibrous histiocytoma, or hyperplastic cutaneous sarcoma, should be removed biopsy.

2. Nodular pruritus: occurs in the extremities of the extremities, multiple hairs and the same size, will not increase to a large extent, itching is obvious without tingling, itching is obvious without tingling, histopathology is epidermis braided or papillary Hyperplasia, no proliferation of collagen fibers and tissue cells in the dermis.

3. Skin leiomyomas: quite similar to skin fibroids, but with pain, histopathological examination showed that the tumor consists of smooth fiber bundles criss-crossed. The nucleus is centered, rod-shaped, blunt at both ends, and collagen fibers are often found between the muscle fiber bundles. Under HE staining, the two fibers are indistinguishable, but stained with Verhoeff-van Gieson? The collagen fibers are red and the muscles are yellow; if stained with Masson's three colors, the collagen is green and the muscles are dark red.

4. The disease needs to be differentiated from malignant melanoma, nodular xanthoma, and keloid.

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