Explore objects with your mouth

Introduction Klüver-Bucy Syndrome (KBS) has been reported to have an incidence of up to 70%, a behavioral abnormality associated with temporal lobe function, similar to KBS in animals with bilateral temporal lobe resection. For example, visual recognition cannot and cannot identify the face of a loved one or the self in the mirror. Exploring objects (mouth exploration) with mouth can also be expressed as compulsive chewing gum or smoking, as well as hand rubbing, touching objects in front of the eyes and excessive appetite, casually eating. In 1939, neuropathologists Klüver and Bucy made an experimental animal model of resected double-leaf monkeys, observed abnormal neurobehavioral changes in monkeys, and described a group of symptoms in animals with bicuspid defects, called Klüver? Bucy syndrome. (Klüver? Bucy syndrome, KBS). In 1975, Marlowe et al first reported the emergence of KBS in humans with herpes simplex encephalitis.

Cause

Reasons for exploring objects with a mouth:

KBS is associated with double temporal lobe injury, especially with double bungee and medial temporal lobe lesions. There are extensive links between temporal lobe and other parts, such as changes in sexual behavior, emotional apathy, and excessive attention to visual stimuli, which are associated with hypothalamic and bilateral amygdala lesions. For example, there are bulimia, excessive attention to visual stimulation, and unusual activities such as exposure to privacy. The symptoms of oral exploration are not typical.

Use the mouth to explore objects (mouth exploration), which can be seen in Alzheimer's disease dementia. Dementia in Alzheimer's disease In the past, people who were 65 years old were called presenile dementia; after 65 years old, they were called senile dementia.

an examination

Related inspection

Brain CT examination of nervous system examination

Exploring the diagnosis of the object with the mouth:

The patients had fever, abnormal mental behavior, polyphagia, and changes in eating habits. Example 1 is also accompanied by oral exploration (biting) and eating something that is not food. Example 2 was accompanied by visual agnosia, docility, enhanced sexual activity, and epilepsy. (2) Both head MRI have bilateral temporal lobe lesions. (3) The number of cells in the cerebrospinal fluid is slightly increased (mainly monocytes) and the protein is increased. (4) EEG: diffuse abnormalities, frontal squatting. (5) Early treatment with acyclovir, the condition gradually improved. Conclusion The clinical features of herpes simplex encephalitis with KBS are: high fever, abnormal behavior, visual agnosia, calm and docile, bulimia, altered eating habits, enhanced sexual activity and oral exploration. Diagnosis is based on clinical presentation, laboratory and imaging studies. KBS is associated with bilateral temporal lobe damage.

KBS has six main manifestations: (1) visual misrecognition, unable to distinguish between family and strangers; (2) increased oral exploration behavior, using mouth licking, biting, chewing or touching with lips; (3) bulimia or Changed eating habits, hunger, eating non-food such as toilet paper, washing powder, leaves, etc.; (4) Excessive attention to visual stimuli, showing a strong reaction, and as the environment changes, as long as the things you see catch, hug or move (5) docile, calm, loss of normal anger and fear response; (6) abnormal sexual activity, often expressed as ambiguity, attempt to stroke the opposite sex, expose the body or masturbation in public places. At least three of the above performances must be available. KBS is also associated with dementia common in Pick disease, Alzheimer disease (AD), adrenal white matter dystrophy, etc., often in the early stage of AD and late AD.

Differential diagnosis

Use the mouth to explore the confusing symptoms of objects:

1. Brain organic mental disorder: due to direct damage to the brain tissue caused by organic psychosis, such as: brain trauma, cerebral hemorrhage, intracranial tumor and other factors.

2, schizophrenia: one of the more common severe mental illness, more common in young adults can be divided into paranoid, youthful, nervous, simple, etc. Common symptoms are: mental paralysis, arrogance, illusion delusion, Excited, incited, and depressed, and so on, the course of the disease has not healed, and the patients and their families are extremely painful.

3, obsessive-compulsive disorder: Obsessive compulsive disorder (OCD), obsessive-compulsive disorder is a kind of neurosis, an anxiety disorder. Patients with this disease are always plagued by a forced mind. The patient repeatedly has obsessive and compulsive behaviors in his life. The patient's self-awareness is intact, knowing that this is unnecessary, even painful, but unable to get rid of it.

The patients had fever, abnormal mental behavior, polyphagia, and changes in eating habits. Example 1 is also accompanied by oral exploration (biting) and eating something that is not food. Example 2 was accompanied by visual agnosia, docility, enhanced sexual activity, and epilepsy. (2) Both head MRI have bilateral temporal lobe lesions. (3) The number of cells in the cerebrospinal fluid is slightly increased (mainly monocytes) and the protein is increased. (4) EEG: diffuse abnormalities, frontal squatting. (5) Early treatment with acyclovir, the condition gradually improved. Conclusion The clinical features of herpes simplex encephalitis with KBS are: high fever, abnormal behavior, visual agnosia, calm and docile, bulimia, eating habits, sexual activity Enhance and explore the mouth. Diagnosis is based on clinical presentation, laboratory and imaging studies. KBS is associated with bilateral temporal lobe damage.

KBS has six main manifestations: (1) visual misrecognition, unable to distinguish between family and strangers; (2) increased oral exploration behavior, using mouth licking, biting, chewing or touching with lips; (3) bulimia or Changed eating habits, hunger, eating non-food such as toilet paper, washing powder, leaves, etc.; (4) Excessive attention to visual stimuli, showing a strong reaction, and as the environment changes, as long as the things you see catch, hug or move (5) docile, calm, loss of normal anger and fear response; (6) abnormal sexual activity, often expressed as ambiguity, attempt to stroke the opposite sex, expose the body or masturbation in public places. At least three of the above performances must be available. KBS is also associated with dementia common in Pick disease, Alzheimer disease (AD), adrenal white matter dystrophy, etc., often in the early stage of AD and late AD.

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