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Baby walk late

Introduction
Cause
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Diagnosis

Introduction

Introduction Clinically, the symptoms are mostly in childhood, most commonly in children under 6 years of age. Boys are more common. The main symptoms are delayed walking, lack of appetite, weight loss, dysplasia, muscle atrophy, weakness or pain, gait, fatigue, and teething. Palpation can also be felt in large tubular bones. The predilection sites are the tibia, femur, tibia, fibula, tibia and ulna. Physical pain occurs sooner or later before the age of 7 and has a special swing gait. The cause is unknown and there is a family morbidity, so it may be related to genetic factors.

Cause

Cause

The cause of the baby walking late:

(A) the cause of the disease: the cause is unknown, there is a family morbidity, so it may be related to genetic factors.

(B) the pathogenesis: Singleton (1956) believes that the thickening of the blood vessel wall causes the lumen to narrow, tissue blood flow is reduced, resulting in bone non-specific cortical thickening, bone and intima new bone formation, bone tissue and The wall of the small arteries adjacent to the subcutaneous tissue is thickened.

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an examination

Related inspection

Bone and joint soft tissue CT examination bone marrow image analysis ESR equation K value

Clinically, the symptoms are mostly in childhood, most commonly in children under 6 years of age. Boys are more common. The main symptoms are delayed walking, lack of appetite, weight loss, dysplasia, muscle atrophy, weakness or pain, gait, fatigue, and teething. Palpation can also be felt in large tubular bones. The predilection sites are the tibia, femur, tibia, fibula, tibia and ulna. Physical pain occurs sooner or later before the age of 7 and has a special swing gait. As we age, the range of bone lesions gradually increases. Muscle weakness is becoming more pronounced and pain is aggravated. The skin of the sick child is rough, and some patients have skin tension on the side of the limb. When the facial bone is involved, the facial skin is tense and shiny. Mandibular hyperplasia, skull base and mastoid hyperplasia, due to thickening of the skull, the appearance of the head increased, but also due to nerve hole deformation can cause nerve pores narrowed and cranial nerve damage, affecting vision and hearing. Good for dental caries, eyeballs and anemia. The limbs are out of proportion to the trunk and the limbs are relatively long. The intelligence is normal. Generally, the lesion develops slowly, and the bone lesion remains until adulthood, while the weakness of the muscle can improve or recover. In some cases, although the bone lesions are significant, there are no clinical symptoms, and no special findings are found in the laboratory tests. In addition, puberty is delayed, and the external genitalia and secondary sexual characteristics are poorly developed.

This symptom mainly occurs in the long bones of the extremities, and the lesions are symmetrical and continue. In some cases, the skull is involved at the same time. There are not many facial bones involved, and occasionally the clavicle, ribs, shoulder blades and mandible are involved. Short bones of the hands and feet and spinal bone involvement are rare.

According to the above clinical manifestations, laboratory tests have no special findings and X-ray examination features, can be diagnosed as the disease.

Diagnosis

Differential diagnosis

Differential diagnosis:

Proliferative periostitis: The periosteum consists of dense connective tissue that coats the surface of the bone other than the articular surface and has many fiber bundles that protrude into the bone. In addition, the tendons and ligaments attached to the bone are woven together with the periosteum at the attachment site. Therefore, the periosteum is very strong in binding to bone. The periosteum is rich in blood vessels and nerves and is distributed in the bone and bone marrow through the nourishing pores of the bone. The medullary cavity and cancellous mesh are also lined with a thin connective tissue membrane called endosteum. The inner layer of the periosteum and the endosteal have the ability to differentiate into osteoblasts and osteoclasts to form new Bone and destruction, transformation of the generated bone, so it is of great significance for the occurrence, growth and repair of bone. In childhood, osteoblasts in the periosteum can continuously produce new bone tissue, thicken the surface of the bone, make the bone thick, and heal after the fracture - bone regeneration, also depends on the osteoblasts of the periosteum. If the periosteal peeling is too much during surgery, the nutrition and regeneration of the bone will cause obstacles, affecting the healing of the fracture end and even causing bone necrosis. In the elderly, the periosteal thinning, the differentiation ability of osteoblasts and osteoclasts is weakened, and the repair function of the bone is reduced.

Diffuse periosteal thickening: Diffuse periosteal thickening is one of the symptoms of periosteal hyperplasia. Perioid hyperplasia (pachydermoperiostosis) is divided into primary and secondary. The primary is autosomal dominant. Secondary is often triggered by liver, lung and digestive tract diseases or malignant tumors. This disease is more common in men.

Periostitis: Periostitis is an infective periosteal injury caused by periosteal and periosteal vasodilatation, hyperemia, edema, or subperiosteal hemorrhage, periosteal hyperplasia, and inflammatory perfusion.