Plasmodium found on blood bone marrow or sputum smear

Introduction One of the symptoms of malaria infection, blood marrow or sputum smear can be found in Plasmodium. Clinical manifestations of typical periodic chills, fever, and sweating can be initially diagnosed. Irregular fever, accompanied by spleen, hepatomegaly and anemia, should be considered the possibility of malaria. The sinister type occurs mostly during the epidemic period, with more urgency, high fever and chill, coma and convulsions. Infants and young children in the epidemic area suddenly have high fever, chills, and coma, and should also consider this disease.

Cause

Plasmodium can be found from blood marrow or sputum smears when infected with Plasmodium.

an examination

Related inspection

Blood test sputum routine examination

Blood marrow or sputum smear to find the diagnosis of Plasmodium

Plasmodium infection.

Epidemiology: There is a history of living or traveling in a malaria endemic area. Fever patients with a history of malaria or recent blood transfusions should be suspected.

Clinical manifestations: Typical periodic chills, fever, and sweating can be initially diagnosed. Irregular fever, accompanied by spleen, hepatomegaly and anemia, should be considered the possibility of malaria. The sinister type occurs mostly during the epidemic period, with more urgency, high fever and chill, coma and convulsions. Infants and young children in the epidemic area suddenly have high fever, chills, and coma, and should also consider this disease.

Laboratory tests: mainly to find malaria parasites, usually found to be diagnosed. Blood tablets to find malaria parasites should be collected at the onset of the cold war, at this time the number of protozoa is many, easy to find. The search should be repeated as many times as needed. And must be looking for thick blood tablets. If the clinical is highly suspected and the blood is repeatedly negative, a bone marrow smear can be used to find the malaria parasite.

Therapeutic diagnosis: The clinical manifestations are very similar to malaria, but no Plasmodium was found after multiple examinations. You can try to kill the red endogenous protozoa (such as chloroquine), and treat the 48-hour fever control, which may be malaria. But pay attention to the chloroquine-resistant strain.

Differential diagnosis

Blood marrow or sputum smear to find confusing symptoms of malaria parasites

General atypical malaria should be differentiated from the following diseases.

Septicemia, malaria, high fever, heat-type retention or relaxation, similar to sepsis. However, the symptoms of systemic poisoning in sepsis are severe; there are focal inflammation or metastatic suppurative lesions; the total number of white blood cells and neutrophils are increased; blood culture can have pathogen growth.

The prevalence of leptospirosis is mostly in the autumn harvest season, and it is closely related to the participation in the autumn harvest. The typical clinical symptoms of "cold fever, soreness, and red eyes and lymph nodes" are available for identification.

Filariasis acute filariasis sometimes needs to be differentiated from malaria, and the identification mainly depends on ectopic lymphangitis, and microfilaria is found in the blood.

Typhoid fever, paratyphoid fever generally does not cause acute onset, persistent high fever, often no chills and sweating, hearing loss, relatively slow pulse, rose rash, leukopenia, disappearance of eosinophils, positive reaction to fat, positive blood or bone marrow culture And so on, it is not difficult to identify.

Acute schistosomiasis comes from endemic areas. It has recently been exposed to plague, has a rash, and eosinophils are significantly increased. The schistosomiasis skin test is positive, and the stool is positive, so it can be diagnosed as schistosomiasis.

Other long-term fever caused by miliary tuberculosis and biliary tract infection should also be identified.

Cerebral malaria is easily confused with epidemic encephalitis, toxic dysentery, and heat stroke. It is often necessary to look carefully for the malaria parasite. Toadstools should also be used for routine and culture. For a while, you can use antimalarial drugs to wait for the results.

Black urine fever should be differentiated from acute hemolytic anemia, such as Hudouhuang; paroxysmal hemoglobinuria.

Diagnose based on:

Epidemiology: There is a history of living or traveling in a malaria endemic area. Fever patients with a history of malaria or recent blood transfusions should be suspected.

Clinical manifestations: Typical periodic chills, fever, and sweating can be initially diagnosed. Irregular fever, accompanied by spleen, hepatomegaly and anemia, should be considered the possibility of malaria. The sinister type occurs mostly during the epidemic period, with more urgency, high fever and chill, coma and convulsions. Infants and young children in the epidemic area suddenly have high fever, chills, and coma, and should also consider this disease.

Laboratory tests: mainly to find malaria parasites, usually found to be diagnosed. Blood tablets to find malaria parasites should be collected at the onset of the cold war, at this time the number of protozoa is many, easy to find. The search should be repeated as many times as needed. And must be looking for thick blood tablets. If the clinical is highly suspected and the blood is repeatedly negative, a bone marrow smear can be used to find the malaria parasite.

Therapeutic diagnosis: The clinical manifestations are very similar to malaria, but no Plasmodium was found after multiple examinations. You can try to kill the red endogenous protozoa (such as chloroquine), and treat the 48-hour fever control, which may be malaria. But pay attention to the chloroquine-resistant strain.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.