Delayed excretion of bromosulfonphthalein

Introduction Delayed excretion of bromosulfonate is an indicator of abnormal liver function, including elevated serum alkaline phosphatase activity, delayed excretion of bromosulfonate, prolonged prothrombin time by plasma albumin, and abnormal bilirubin elevation globulin. Liver damage can be caused mainly by parasites (Schistosoma, amoeba), Leptospira, bacteria, and viruses; among them, viruses are most common (such as viral hepatitis). Chemical poisoning such as carbon tetrachloride, chloroform, phosphorus, antimony, arsenic, etc., can often destroy the enzyme system of liver cells, causing metabolic disorders. Blood circulation disorders such as chronic heart failure cause liver congestion and hypoxia. When there is insufficient nutrition and lack of biliary methionine, it can cause liver fatty changes.

Cause

Abnormal liver function caused by various reasons.

1. Infection: Parasites (Schistosomiasis, Amoeba), Leptospira, bacteria, and viruses can cause liver damage; especially viruses are most common (such as viral hepatitis).

2, chemical poisoning such as carbon tetrachloride, chloroform, phosphorus, antimony, arsenic, etc., often destroy the enzyme system of liver cells, causing metabolic disorders.

3, blood circulation disorders such as chronic heart failure, causing liver congestion and hypoxia.

4, lack of nutrition, lack of biliary methionine, methionine, can cause liver fatty changes. This is because the transport of intrahepatic fat must first be converted to phospholipids (primarily lecithin), which is an essential component of lecithin. Methionine supplies a methyl group that synthesizes cholesteric. When these substances are deficient, the removal of fat from the liver is blocked, causing fatty changes in the liver.

an examination

Related inspection

General radiography examination of liver, gallbladder, spleen CT examination

Delay in excretion of bromosulfonate:

CT examination: CT examination of liver, gallbladder and spleen.

General radiography: General radiography can be taken on the skull, chest, abdominal plain, bones and joints of the limbs. The film plays an important role in the diagnosis work, and has the following advantages compared with the perspective:

1. The image of the part to be inspected is permanently retained on the film for analysis, discussion and review.

2. Can be saved as scientific research materials.

3. The film can show the fine structure, such as the early source of more than 2mm is more clear than the perspective.

4. The film can check the thick part of the human body and make the patient receive less X-rays.

Differential diagnosis

Differential diagnosis of delayed confusing symptoms of bromosulfonate excretion:

1. Various viral hepatitis, fatty liver, cirrhosis, and severe liver disease are the most common causes of abnormal liver function.

2, infected parasites (schistosomiasis, Clonorchis sinensis, amoeba), Leptospira, bacteria, viruses can cause liver damage; especially viruses are most common. Such as: liver echinococcosis, liver bacterial infection, hepatitis B, etc., is also the cause of abnormal liver function.

3, biliary obstruction, such as stones, tumors, mites and other cholestasis, if the time is too long, due to the retention of bile on the damage of liver cells and intrahepatic dilated bile duct sinus compression caused by hepatic ischemia, causing hepatocytes Degeneration and necrosis are the causes of abnormal liver function.

4, chemical poisoning often destroys the enzyme system of liver cells, causing metabolic disorders, or inhibiting the oxidative phosphorylation process, reducing ATP production, leading to degeneration and necrosis of liver cells, leading to abnormal liver function; some drugs, such as chlorpromazine, For salicylic acid, isoniazid, certain iodine drugs and antibiotics, even a therapeutic dose can cause liver damage in a few people. It is the most common cause of transient liver dysfunction, which may be related to allergies. Liver function can be restored within a few days after stopping the drug.

5, blood circulation disorders, such as chronic heart failure, causing liver congestion and hypoxia, is also one of the causes of abnormal liver function.

6, genetic defects, some liver diseases are genetic diseases caused by genetic defects. Hereditary hemochromatosis, cystic fibrosis, a1-antitrypsin deficiency, Wilson's disease, etc. are the most common and important congenital liver diseases, which are all causes of abnormal liver function.

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