Painless hard solid nodules

Introduction In the first diagnosis of some patients with medullary thyroid carcinoma, the main manifestation is the painless hard solid nodules of the thyroid. The main cause of medullary thyroid carcinoma is the RET proto-oncogene mutation. Symptoms of medullary thyroid carcinoma should be alarmed when unilateral or bilateral thyroid masses, poor breathing, difficulty swallowing, hoarseness, convulsions of the hands and feet, and carcinoid syndrome. Women, who are between the ages of 30 and 60, have a family history of thyroid parathyroid glands and adrenal tumors, and are susceptible to medullary thyroid carcinoma.

Cause

Chinese medicine believes that this disease is mainly caused by emotional anger, dissatisfaction and lack of righteousness, resulting in turbidity, dampness, blood stasis and evil fire in the neck.

an examination

Related inspection

Thyroglobulin

Clinical manifestations: Most patients in the first visit, the main performance is the painless hard solid nodules of the thyroid, local lymphadenopathy, sometimes lymph node enlargement becomes the first symptom, such as with heterologous ACTH, can produce different symptoms, serum Calcitonin levels are significantly increased, which is the biggest feature of the disease, so calcitonin becomes a diagnostic marker, more than 0.6ng / ml, should consider C cell proliferation or medullary carcinoma, due to calcitonin on blood calcium The level of regulation is far less powerful than parathyroid hormone, as well as ganglionoma or mucosal neuroma, which is MEN.

At the time of physical examination, the thyroid mass is solid, the boundary is unclear, and the surface is not smooth. The family and MEN2 patients can be bilateral thyroid masses, and the masses have better activity. After the late invasion of adjacent tissues, they are more fixed, such as hoarseness.

Differential diagnosis

The diagnosis of thyroid cancer is expensive in the early days. It is necessary to exclude the possibility of thyroid cancer in the clinical diagnosis of thyroid nodules such as hard and uneven nodules with cervical lymph nodes, recurrent laryngeal nerve palsy or previous cancer with a history of neck reflex. The possibility is also great. As in the multiple nodules of the thyroid, a nodule is particularly prominent and hard. It is also suspected of having thyroid cancer. In addition, if the thyroid itself has an asymmetrical enlargement or induration, it increases rapidly or has been fixed. All should consider the possibility of thyroid cancer.

Thyroid nodules are masses in the thyroid gland that move up and down with the thyroid gland as they swallow. They are common clinical conditions and can be caused by a variety of causes. Thyroid nodules can be divided into single and multiple nodules. The size, location, texture, function and clinical significance of nodules vary.

Clinical manifestations: Most patients in the first visit, the main performance is the painless hard solid nodules of the thyroid, local lymphadenopathy, sometimes lymph node enlargement becomes the first symptom, such as with heterologous ACTH, can produce different symptoms, serum Calcitonin levels are significantly increased, which is the biggest feature of the disease, so calcitonin becomes a diagnostic marker, more than 0.6ng / ml, should consider C cell proliferation or medullary carcinoma, due to calcitonin on blood calcium The level of regulation is far less powerful than parathyroid hormone, as well as ganglionoma or mucosal neuroma, which is MEN.

At the time of physical examination, the thyroid mass is solid, the boundary is unclear, and the surface is not smooth. The family and MEN2 patients can be bilateral thyroid masses, and the masses have better activity. After the late invasion of adjacent tissues, they are more fixed, such as hoarseness.

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