Painless mouth ulcers

Introduction Oral ulcers are superficial ulcers that occur on the oral mucosa. They can vary in size from rice to soybeans, round or oval, ulcers are concave, and the surrounding is congested. It can cause pain due to irritating food, usually one or two. You can heal yourself in the week. Painless oral ulcers are one of the criteria for the diagnosis of Wegener's granuloma proposed by the American College of Rheumatology. Wegener's granuloma is characterized by progressive necrotizing granulomatosis and extensive small vasculitis. Mainly involving the respiratory tract, kidney, skin and other organs to produce the corresponding clinical manifestations.

Cause

It is not clear that since most patients have upper respiratory symptoms first, followed by glomerulonephritis, some people think that the slow-separated protein after upper respiratory tract infection can become an allergen, causing the body to develop an allergic reaction and cause a whole disease. It has been reported that long-term survival is achieved with trimethoprim (TMP) and iodomethylisoxazole (SMZ), which is associated with microbial infection. Half of the cases were positive for rheumatoid factor, with high gamma globulinemia and circulating immune complexes, and autoimmune diseases with cellular immune intervention.

an examination

Related inspection

Oral endoscopic 3-methoxy adrenaline

Histopathological examination:

1. A necrotizing granuloma occurs in the upper or lower respiratory tract.

2, the lung, skin has primary focal necrotizing vasculitis.

3, focal necrotizing renal tubular nephritis.

In order to be able to diagnose early, check the following conditions and repeat the pathological examination if necessary:

1, chronic rhinitis and / or sinusitis with mucosal erosion or granulation tissue proliferation.

2, eye, oral mucosal ulcers, necrosis or granuloma.

3. There are variable nodular shadows or holes in the lungs.

4, the skin has purpura, nodular invasive plaque, necrosis, ulcers and so on.

Differential diagnosis

Intractable oral ulcer means that after strict medical treatment, the ulcer still cannot heal, the clinical symptoms persist, or it is repeated, which affects the daily life and work of the patient. In the mucous membranes of the lips, cheeks, soft palate or gums, single or multiple round or oval ulcers of different sizes occur, the surface is covered with gray or yellow pseudomembrane, the central depression, the boundary is clear, and the surrounding mucosa is red and micro Swelling, local burning pain is the main feature.

Benign ulcer changes: limited defects or ulceration of the skin or mucosal surface tissue. Ulcer is a localized defect or ulceration of the skin or mucosal surface tissue. The surface is often covered with pus, necrotic tissue or ecdysis. The scar is left behind, which can be caused by infection, trauma, nodules or tumor rupture. Its size, shape, depth, development process, etc. are also inconsistent. Oral ulcers can be divided into benign and malignant.

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