Physiological jaundice

Introduction Astragalus is a common clinical symptom in the neonatal period. Because of its different pathogenesis, it can be either a physiological phenomenon or a pathological phenomenon. Clinically, the total serum bilirubin in term infants exceeds 205.2 mol/L (12 mg/dl), and the preterm infants exceed 256.5 mol/L (15 mg/dl) is called hyperbilirubinemia. Astragalus is due to the high concentration of bilirubin in the blood, so that the skin and mucous membranes appear as seen by the naked eye. In fact, most newborns born soon may have varying degrees of jaundice, which is called physiological jaundice, and is related to the characteristics of neonatal bilirubin metabolism.

Cause

There are two main reasons for the development of neonatal physiological jaundice: First, the characteristics of neonatal bilirubin metabolism are determined. After the birth of the fetus, the blood oxygen partial pressure suddenly rises, the red blood cells destroy quickly, and more bilirubin is produced. The neonatal liver enzyme activity is low, and it is impossible to remove too much bilirubin, thus causing jaundice.

On the other hand, neonatal jaundice occurs mostly in breast-fed children. Therefore, the chemicals and hormones in breast milk are another cause of neonatal jaundice. However, this jaundice is mostly physiological jaundice and is not harmful to newborns. Mothers should be encouraged to continue breastfeeding.

an examination

Related inspection

Erythrocyte serum total bilirubin direct bilirubin

The serum bilirubin assay exceeded 34.2 mol/L (2 mg/d1) within 1 week after birth. The serum bilirubin value of full-term neonatal jaundice does not exceed 205.23mol/L (12mg/d1), and premature infants are heavier than full-term infants, with peak values of 17l-205mol/l (10~12mg/d1), but Not more than 256.5 mol/L (15 mg/d1).

Differential diagnosis

Different from pathological jaundice, pay attention to observe the time and evolution of jaundice. For example, jaundice appears early, appears within 24 hours after birth, jaundice subsides late, continues to retreat, or reappears after physiological jaundice subsides, or jaundice continues to increase, etc. Etc., are all pathological jaundice. Clinically associated with abnormal symptoms and signs of jaundice, are pathological jaundice. Pathological jaundice can cause bilirubin encephalopathy, and should actively identify the cause and actively treat the disease.

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