Systemic vascular damage

Introduction Systemic vascular damage caused by various pathological changes can be seen in allergic purpura, dengue fever and the like.

Cause

Caused by various pathological changes, can be seen in allergic purpura, dengue fever and so on. Any open or indirect violent invasion of blood vessels may result in open or closed vascular injury. The causes of vascular injury are complex and the classification is also inconsistent. According to the force situation, it can be divided into direct damage and indirect damage; according to the injury factor can be divided into sharp damage and blunt injury; according to the continuity of the damaged blood vessel can be divided into complete fracture, partial fracture and vascular contusion; The degree of vascular injury can be divided into light, medium and heavy injuries. Of course, no matter which classification, it can't fully summarize the whole picture of its vascular injury.

an examination

Related inspection

Blood analyzer to check blood test for blood and bone marrow bacteria

Pathological changes in dengue hemorrhagic fever are systemic microvascular damage leading to plasma protein exudation and hemorrhage.

Allergic purpura is a syndrome characterized by small vessel damage as a major pathological system. It is characterized by skin purpura, hemorrhagic gastroenteritis, arthritis and kidney damage. Arterial Doppler examination can detect abnormalities in arterial blood flow, such as reduced sound, disappearance, systolic murmur (aneurysm), or continuous murmur (arteriovenous fistula).

Differential diagnosis

First, dengue fever should be differentiated from influenza, measles, scarlet fever, drug eruption; dengue shock syndrome of dengue hemorrhagic fever should be associated with jaundice hemorrhagic leptospirosis, epidemic hemorrhagic fever, sepsis, epidemic cerebrospinal membrane Identification of inflammation and yellow fever.

Second, the differential diagnosis of allergic purpura

1, idiopathic thrombocytopenic purpura: according to the shape of skin purpura is not higher than the skin, distribution asymmetry and platelet count reduction, it is not difficult to identify. Allergic purpura rashes are associated with angioedema, urticaria or erythema multiforme.

2. Septicemia: The rash caused by meningococcal septicaemia is similar to that of purpura, but the symptoms of this disease are severe, the white blood cells are obviously increased, and the smear test smear at the rash is positive.

3, rheumatoid arthritis: both can have joint swelling and pain and low fever, it is difficult to identify before the appearance of purpura, with the development of the disease, the skin appears purpura, it is helpful to identify.

4, intussusception: more common in infants and young children. If the child bursts into tears, the abdomen touches the mass, and the abdominal muscles should be suspected of being sick. Barium enema perspective can be identified. However, allergic purpura can be accompanied by intussusception, so it should be noted.

5, appendicitis: both can appear umbilical and right lower abdominal pain with tenderness. However, the allergic purpura is not tense, and the skin has purpura, which can be identified.

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