Skin and mucous membranes

Introduction The skin and mucous membrane protect the human body, so that the human body forms a closed system to the outside world. When harmful substances are to invade the human body, the skin and mucous membranes first block the external pathogenic factors outside the body. Therefore, skin and mucous membranes are the first line of defense against infection. However, when the invasive amount of harmful substances exceeds the endurance of the mucous membrane, it causes damage such as redness and discoloration of the skin and mucous membranes.

Cause

The immune response is related to environmental pollution, drugs, chemical agents, and the like. Lesions can involve arteries, veins, and capillaries, and can invade multiple systems throughout the body, making clinical manifestations diverse and most serious coronary lesions, often the leading cause of death.

an examination

Related inspection

Serum immunoglobulin (Ig) C-reactive protein (CRP) erythrocyte sedimentation rate (ESR)

Skin and mucous membrane manifestations: pleomorphic urticaria-like, erythema or scarlet fever-like rash in the trunk, no blister or blister. The extremities of the extremities showed solid swelling at the beginning and the membranous peeling of the fingers during the recovery period. Conjunctival hyperemia of both eyes, no purulent secretions and tears, dry lips, flushing, splitting, bayberry tongue, diffuse redness in the oral and pharyngeal mucosa without ulceration and pseudomembrane formation.

Laboratory examination of increased white blood cells, increased neutrophils, increased erythrocyte sedimentation rate, increased C-reactive protein, increased immunoglobulin, increased transaminase in some cases, and ECG and echocardiographic changes in patients with heart damage.

Differential diagnosis

Skin Mucosal Lymph Node Syndrome Skin mucosal lymph node syndrome, also known as Kawasaki disease, is a connective tissue disease characterized by allergic systemic small vessel vasculitis. Mainly manifested as acute fever, skin and mucous membrane lesions and lymphadenopathy. More common in infants and young children. The incidence of the disease in China has increased significantly in recent years.

Chronic mucocutaneous candidiasis: A bacterial immunodeficiency disease of persistent Candida infection of the skin, mucous membranes, hair and nails.

Skin and mucous membrane bleeding is a disease caused by abnormal blood vessel wall function, abnormal platelet number or dysfunction, and coagulopathy.

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