Skin flaking and leading to exfoliation

Introduction

Introduction Exfoliative dermatitis-type drug eruptions generally occur between the 3rd and 7th day after onset of the disease, which can cause skin debris and cause exfoliation, especially in the skin of the palms and soles.

Cause

Cause

Mostly caused by barbiturates, sulfonamides, phenytoin, phenylbutazone, sodium salicylate, penicillin, streptomycin and other drugs. Most cases occur after long-term use.

Examine

an examination

Related inspection

Urine routine blood test

The incubation period of the first-onset is about 20 days. Some cases are caused by measles-like, scarlet-like or eczema-type drug eruptions. The lesions are caused by measles-like or scarlet-like fever, and gradually become diffuse into the whole body. Flushing, swelling, especially on the face and hands and feet, may have herpes or blisters, accompanied by erosion, a small amount of exudation, 2-3 weeks, the skin redness and swelling gradually subsided, the body appears scaly or deciduous desquamation, the hands and feet are Gloves or sock-like exfoliation, hair, finger (toe) can fall off, regenerate after recovery, redness and swelling of the lips and mouth, or blisters, erosion, pain and eating, conjunctival congestion, edema, photophobia, increased secretion, Corneal ulcers can occur when heavy, and the superficial lymph nodes often enlarge, may be associated with bronchial pneumonia, sexual hepatitis, peripheral blood cells can be increased or decreased, and even granulocytosis.

Diagnosis

Differential diagnosis

1, exfoliative dermatitis: a rare and serious skin disease. Also known as erythroderma. It is characterized by diffuse erythema swelling and desquamation in the whole body or large areas of the skin.

2, rice bran-like desquamation is common in measles;

3, flaky desquamation is common in scarlet fever;

4, silvery white scaly desquamation found in psoriasis.

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