Cystoid plaque

Introduction In patients with apocrine adenocarcinoma, the lesions were single or multiple, with nodular or cystic plaques, 1.5 to 8 cm in diameter. Apocrine carcinoma is rare. Common in the apocrine gland distribution area, mainly in the armpit, the eyelids and external auditory canal have deformed apocrine glands, Moll glands and parotid glands. Single or multiple lesions, nodular or cystic plaques, 1.5 to 8 cm in diameter, the surface of the skin is red or purple, even broken, although some apocrine glands only local invasion, but others transferred to the local Lymph nodes, some patients can also die due to extensive metastasis.

Cause

an examination

Related inspection

Cellular immunohistochemistry, cell histochemical staining, CT examination

Auxiliary inspection:

Histopathology: The tissue appears to be a well-differentiated, moderately or poorly differentiated adenocarcinoma. The well-differentiated apocrine adenocarcinoma has a limited degree of nuclear atypicality and invasiveness. There are well-developed glandular cavities with cystic and branched lumens. The cytoplasm of the tumor cells is strongly acidic, at least in some areas with apocrine glands. Decapitation secreted evidence. In addition, the cytoplasm of the tumor cells contains PAS-positive, amylase-resistant granules, and no myoepithelial cells. Moderate or poorly differentiated apocrine adenocarcinoma, it is difficult to identify the source of apocrine glands.

Histochemistry and immunohistochemistry contribute to the judgment of apocrine-derived tumors. 40% to 50% of apocrine adenocarcinoma, positive staining with Prussian blue. The giant cystic disease liquid protein 15 (GCDFP-15) is strongly positive.

Differential diagnosis

Differential diagnosis of cystic plaques:

1. Generalized red plaque: is a red plaque that is caused by various factors. It can be seen in seborrheic dermatitis, which occurs in areas with more sebaceous glands, such as the head, face, back of the ear, armpits, chest, scapula, groin, perineum, etc. The initial rash is red papules or patches that fuse with each other and are covered with greasy scales or jaundice.

2, hard and non-recessed edema of the anterior and posterior pedicles: the hard non-depressed edema of the anterior and posterior tibia is a diffuse type of mucinous edema before the iliac crest: the anterior and anterior Depressed edema plaque.

3, large plaques in the chest: dark-colored filariasis patients are more common in outdoor work and often contact with such rot. Can be expressed as shallow ulcers, ecchymoses, brownish black spots or verrucous hyperplasia, consciously itchy or mild pain, and some may have no symptoms. Subcutaneous tissue type of dark filamentous mold often has isolated, deep subcutaneous or muscular abscesses or cysts, lesions can be apricot nucleus large or a few centimeters, or even large plaques throughout the chest.

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