Endocrine dysfunction

Introduction The classic concept of the endocrine system refers to the endocrine gland of a group of specialized cells. They include the pituitary gland, thyroid gland, parathyroid gland, adrenal gland, gonad, islet, thymus and pineal gland. These glands secrete high-performance organic chemicals (hormones) that transmit chemical information to their target cells, target tissues, or target organs through blood circulation, exerting excitatory or inhibitory effects. Hormone is also called endocrine as the first messenger. One of the declines in endocrine function is primary dysfunction: the lesion is in the target gland of the hormone secretion, and the target gland cells are destroyed by bleeding, ischemia, infection, etc., and the secretion of hormones is too small, resulting in a decrease in endocrine function. Primary hypothyroidism caused by chronic lymphatic thyroiditis. Second, secondary dysfunction: lesions in the pituitary, due to the lack of pituitary hormones or physiological stimulating factors caused by the secretion of target gland hormones, such as secondary hypothyroidism caused by Sheehan's disease. Third, the third sexual dysfunction: the lesion in the hypothalamus, lack of hypothalamic release factor and decreased secretion of pituitary and its target gland.

Cause

Primary hypothyroidism, secondary hypothyroidism, hypothalamic release factor deficiency, and target glandular lesions that secrete hormones.

The human body has an endocrine system that secretes various hormones and the nervous system to regulate the metabolism and physiological functions of the human body. Under normal circumstances, various hormones are balanced, such as breaking the balance for some reason (some hormones are too much or too little), which causes endocrine disorders, which will cause corresponding clinical manifestations. Endocrine disorders can occur in both men and women.

1, physiological factors: experts pointed out that the body's endocrine hormones will generally be dysregulated with age. Usually the younger the less the endocrine. With age, women tend to ignore it. Some women's endocrine disorders are derived from heredity.

2, nutritional factors: adequate and appropriate nutrition is the basic guarantee for the body to maintain normal physiological functions, and now many female friends lose weight, food intake is insufficient, endocrine and other issues will appear one by one.

3. Environmental factors: Severe environmental pollution is another major factor in female endocrine disorders. In particular, toxic gases in the air enter the human body and undergo a series of chemical reactions, which indirectly lead to many problems such as menstrual disorders and endocrine disorders.

4. Emotional factors: Psychology is also an important reason. Experts at Beijing Jiayuan Hospital said that if people are in a state of tension, they will be reflected to the nervous system, causing disorder of hormone secretion.

an examination

Related inspection

Endocrine function test

Serological tests for six endocrine tests are generally performed on the third day of the menstrual cycle. If it is because of amenorrhea, you can check it at any time; if it is a special case of time, you can check it at any time, but you must indicate the specific time, such as the specific time of the menstrual cycle. Because there are four types of follicular phase, ovulation period, luteal phase and menopause in the menstrual cycle, the normal values of these types are different. Does not explain the specific time of the menstrual cycle, there is no way to judge whether it is normal or not.

In the six endocrine examinations, the items examined are different and the methods of attention are different. The contents of the inspection can be checked in full or in a single inspection, but many hospitals are currently in full inspection. All inspections should pay attention to:

1. Check testosterone, which is 2 ml of venous serum. The commonly used method is radioimmunoassay. After separating serum, it can be determined.

2. Check estrogen (estradiol), progesterone, follicle stimulating hormone, and also check after separation of venous serum, which requires 2 ml.

3. Check luteinizing hormone, although it is also radioimmunoassay, but because luteinizing hormone is pulsed secretion, specimen collection is best collected 3-4 times within 1 hour, and then mixed together for measurement, which is more accurate.

4. Prolactin should be checked on an empty stomach and serum should be taken around 9 am.

Differential diagnosis

Should be differentiated from renal edema, anemia, congestive heart failure and so on. According to rT3 and the patient's primary disease manifestations, with low T3 syndrome, hypothyroidism and galactorrhea should be differentiated from prolactinoma.

1 functional diagnosis.

2 pathological diagnosis, including nature and location.

3 The cause of the diagnosis, when the cause, pathology, etc. are difficult to be clear, only clinical diagnosis can be obtained. Diagnostic basis includes: medical history, symptoms, signs, laboratory data, X-ray, CT and other general information, as well as special examinations of glandular secretion function and experimental results and related pathological examination results.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.