Gastric mucosal injury

Introduction The entire inner surface of the stomach is covered with a layer of mucosal tissue that secretes mucus, forming a mucous-mucosal barrier of the stomach to protect the stomach tissue. Gastric mucosal injury is more common in gastritis and gastric ulcer.

Cause

Often due to chemical factors (smoking, drinking, strong tea, coffee and drugs that stimulate the gastric mucosa such as aspirin, indomethacin, etc.), physical factors (too cold, too hot, too rough food or overeating, etc.), Caused by factors such as bacteria or their toxins.

an examination

Related inspection

Fiber gastroscope stomach examination

Gastroscopic examination, observing the color, bleeding point, congestion and erosion of the gastric mucosa. Degrees, before and after changes, according to the degree of disease is divided into light, moderate and severe damage.

Gastrointestinal contrast-enhanced ultrasonography can clearly show the structural level of the stomach wall, which has certain diagnostic value for acute gastric mucosal injury.

Regardless of the invasive factors, the gastric mucosal damage caused by it is a programmed injury response: firstly, the superficial mucosal damage is caused by the exfoliation of the epithelial epithelium; the damage is further developed, and the microvascular endothelial cell injury will lead to mucosal ischemia and deficiency. Oxygen, tissue necrosis, resulting in deep mucosal damage (erosive or ulceration).

Differential diagnosis

Atrophic changes in gastric mucosa: atrophic changes in gastric mucosa are clinical manifestations of gastric mucosal inflammatory lesions and chronic atrophic gastritis.

Thickening of gastric mucosa: one of the clinical manifestations of "chronic atrophic gastritis" (intestinal, atypical hyperplasia), chronic atrophic gastritis is a common stomach disease. Arteriosclerosis, insufficient blood flow to the stomach, and hobby of tobacco and tea are all likely to impair the barrier function of the gastric mucosa and cause chronic atrophic gastritis. In atrophic gastritis, the gastric mucosa is atrophied and replaced by intestinal epithelial cells, ie intestinal metaplasia; inflammation continues to evolve, cell growth is atypical, ie, metastasis; even cell proliferation and carcinogenesis.

Gastric mucosa shedding: The gastric mucosa is relatively relaxed. When the stomach contracts, the gastric mucosa near the pylorus is removed into the duodenal bulb. The clinical symptoms are symptoms of gastritis. Gastric mucosal congestion: Gastroscopic examination of acute gastritis revealed extensive hyperemia of the mucosa, edema, erosion, hemorrhage, sometimes visible mucus spots on the mucosal surface or bile reflux. When Hp is infected with gastritis, micronodular formation of gastric mucosa can also be seen.

Gastroscopic examination, observing the color, bleeding point, congestion and erosion of the gastric mucosa. Degrees, before and after changes, according to the degree of disease is divided into light, moderate and severe damage.

Gastrointestinal contrast-enhanced ultrasonography can clearly show the structural level of the stomach wall, which has certain diagnostic value for acute gastric mucosal injury.

Regardless of the invasive factors, the gastric mucosal damage caused by it is a programmed injury response: firstly, the superficial mucosal damage is caused by the exfoliation of the epithelial epithelium; the damage is further developed, and the microvascular endothelial cell injury will lead to mucosal ischemia and deficiency. Oxygen, tissue necrosis, resulting in deep mucosal damage (erosive or ulceration).

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.