The secretion of lacrimal glands, sweat glands and salivary glands first increases and then decreases

Introduction For the symptoms of neurotic food poisoning (botulism), the autonomic nerve endings are stimulated and then inhibited, so the secretion of lacrimal gland, sweat gland and parotid gland increases first and then decreases. Because the neck muscles are weak, the head tends to lean toward one side. In the course of the disease, he is conscious, feels normal, and does not have fever. Often accompanied by constipation, bloating, urinary retention. The light gradually recovered within 5 to 9 days, but the general weakness and eye muscle spasm lasted for a long time. Severe rescue did not promptly die most, the mortality rate was 30% to 60%. The causes of death were mostly respiratory failure caused by medulla oblongata, cardiac insufficiency and secondary infection caused by aspiration pneumonia. The first symptom of infant patients is often constipation, rapid cranial nerve palsy, sudden death due to sudden central respiratory failure (Sudden Sudden Death Syndrome (SIDS)).

Cause

Mainly due to dysfunction of nerve endings, mostly caused by food poisoning.

an examination

Related inspection

Lacrimal gland examination

1. Epidemiological data

There are suspicious foods, especially bacon, canned foods such as bacon or fermented beans and noodle products.

2. Clinical manifestations

There are special neurological symptoms and signs, such as eye muscle spasm, swallowing, chewing, difficulty in pronunciation, difficulty breathing.

3. Laboratory inspection

Anaerobic bacteria culture is carried out with suspicious food to isolate pathogenic bacteria. Or use animal tests to check botulinum toxins in patients' serum and suspected foods.

Differential diagnosis

Identify symptoms of poisoning early:

1, gastrointestinal irritation symptoms: a history of suspicious food, sudden onset, the beginning of the disease may have headache, dizziness, dizziness, fatigue, nausea, vomiting, mouth and throat flushing, accompanied by sore throat.

2, nerve damage symptoms: Later, sarcoplasmic toxins cause intraocular and extraocular muscle spasm, eye symptoms, such as blurred vision, double vision, drooping eyelids, dilated pupils, disappearance of light reflection; such as pharyngeal muscle spasm, then Difficulty breathing. Due to the weakness of the cervical muscles, the head leans forward or leans toward one side; the tendon reflection can be reduced in symmetry.

3, autonomic nerve damage: the performance of the first excitement and inhibition, the initial secretion of lacrimal gland, sweat gland and parotid gland increased and then decreased. Blood pressure first rises normally and then rises. The pulse is slow and fast. Often there are intractable excretion, bloating, and urinary retention. In the course of the disease, he is conscious, feels normal, and does not have fever. The light gradually recovered within 5 to 9 days, but the general weakness and eye muscle spasm lasted for a long time.

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