Severely congested red lips

Introduction Mucocutaneous lymph node syndrome (MCLS), also known as Kawasaki disease, is an acute febrile rash pediatric disease characterized by systemic vasculitis. Due to the serious cardiovascular disease, this disease can cause people to pay attention.

Cause

The disease is a certain epidemic and landlord, the clinical manifestations of fever, rash, etc., presumably related to infection. It is generally believed to be a variety of pathogens, including Epstein-Barr virus, retrovirus, or Streptococcus, Propionibacterium infection.

an examination

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Bacteriology test blood routine

The main symptoms are common persistent fever, 5 to 11 days or longer (2 weeks to 1 month), body temperature often reaches 39 ° C or more, antibiotic treatment is invalid. Common bilateral conjunctival congestion, lip flushing, cleft palate or bleeding, see the bayberry-like tongue. Hard edema in the hands, flushing of the palms and soles of the feet early, 10 days after the emergence of characteristic toe-end large-scale peeling, appearing at the junction of the nail bed skin. There is also an acute non-suppurative transient cervical lymph node swelling, the most prominent neck, the diameter of about 1.5cm or more, mostly appear in one side, slightly tenderness, occurred within 3 days after fever, and self-healing after a few days. Shortly after fever (about 1-4 days), there is a maculopapular rash or a polymorphous erythematous rash. Occasionally, a herpes-like rash is more common in the trunk, but no herpes and crusting, and it subsides in about a week.

Differential diagnosis

It should be differentiated from various rash infectious diseases, viral infections, acute lymphadenitis, rheumatoid diseases and other connective tissue diseases, viral myocarditis, rheumatoid carditis.

The difference between this disease and scarlet fever is: 1 rash begins on the third day after onset; 2 rash morphology is close to measles and polymorphic erythema; 3 premature age is infant and younger children; 4 penicillin has no effect.

The difference between this disease and juvenile rheumatoid disease is: 1 shorter fever period, shorter rash; 2 hard swelling of hands and feet, showing frequent flushing; 3 types of rheumatoid factor negative.

The difference from exudative polymorphic erythema is: 1 eye, lip, no purulent secretion and pseudomembrane formation; 2 rash does not include blisters and scars.

The difference with systemic lupus erythematosus is: 1 rash is not significant on the face; 2 white blood cells and platelets are generally elevated; 3 anti-nuclear antibodies are negative. 4 good age is more common in infants and boys.

There are many similarities with the symptoms of infantile nodular multiple arteries, but the incidence of MCLS is more, the course of disease is shorter, and the prognosis is better. The relationship between the two diseases remains to be studied.

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