Diffuse laryngeal mucosal hypertrophy, uneven

Introduction Lung amyloidosis affects the larynx, diffuse mucosal hypertrophy, unevenness, or smooth and hard polypoid mass, or obvious local ulcer surface or follicular hyperplasia. Vocal cords and epiglottis are also often involved. For some people who are exposed to chemical irritants, the incidence is higher, and the smoking population is also higher. For women, in addition to their own working environment, passive smoking can not be underestimated. The age of onset is 9 to 90 years old, and the ratio of male to female is 1:1.

Cause

The larynx is the most common site of focal amyloidosis in the respiratory tract and is reported to account for approximately 75%. The amyloidosis of the larynx accounts for about 1% of the benign tumor of the larynx. The age of onset is 9 to 90 years old, and the ratio of male to female is 1:1. False vocal cords are the most commonly affected parts, and vocal cords and epiglottis are often involved.

an examination

Related inspection

Otolaryngology CT examination

The main symptoms are hoarseness, bleeding, and even fatal upper respiratory tract bleeding. Severe cases may have symptoms of upper respiratory tract obstruction such as inspiratory dyspnea and throat. Through the laryngoscope, diffuse mucosal hypertrophy, unevenness, or a smooth and hard polypoid mass can be seen. X-ray films, bronchoscopy, lung biopsy, high-resolution CT and bronchoscopy of the lungs can be performed according to clinical symptoms to determine whether it is pulmonary amyloidosis.

Differential diagnosis

Once the laryngeal amyloidosis is diagnosed, other organs should be examined for involvement. X-ray films, bronchoscopy, lung biopsy, high-resolution CT and bronchoscopy of the lungs can be performed according to clinical symptoms to determine whether it is pulmonary amyloidosis. It is not uncommon for the lower airway amyloidosis to invade the throat at the same time, accounting for about 12% to 40%. Occasionally other organs such as lacrimal glands, lymph nodes, stomach or skin amyloidosis are involved in the throat. The main symptoms are hoarseness, bleeding, and even fatal upper respiratory tract bleeding. Severe cases may have symptoms of upper respiratory tract obstruction such as inspiratory dyspnea and throat. Through the laryngoscope, diffuse mucosal hypertrophy, unevenness, or a smooth and hard polypoid mass can be seen.

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