Iris heterochromia

Introduction Iris heterochromia refers to the iris of the two eyes showing different color traits. The color of the eye, especially the color of the iris, is determined by the pigmentation and distribution of the iris tissue. Therefore, any factor affecting the above pigment distribution during the formation process will result in a difference in eye color. The iris of the two eyes is very rare in humans. Usually this is an indicator of eye disease, such as chronic iritis or diffuse iris melanoma, but it may also be a normal variant. Iridescent color is common in some specific dog and cat breeds, such as Siberian ferrets, Australian Shepherd dogs, Border Collies, and White Persian cats, mainly due to crossbreeding.

Cause

Congenital aspects, mainly the difference in the color of the iris of the two eyes, may be related to heredity. Since the color of the iris of the eye is affected by heredity, if one of the parents of the offspring has blue eyes and the other has gray eyes, the two offspring may have a pair of blue eyes or a pair of gray eyes. However, it is also possible that the iris of one eye is blue and the other side is gray. This may be related to Waardenburg Syndrome or Piebald Syndrome.

The condition of the day after tomorrow may be due to the involvement of Horner Syndrome or Iris dermatitis, which causes the iris to become damaged and shrink.

It may also be caused by a deficiency in iris pigmentation or related to genes.

an examination

Related inspection

Ophthalmoscopy

The iris of the two eyes is very rare in humans. Usually this is an indicator of eye disease, such as chronic iritis or diffuse iris melanoma, but it may also be a normal variant. Iridescent color is common in some specific dog and cat breeds, such as Siberian ferrets, Australian Shepherd dogs, Border Collies, and White Persian cats, mainly due to crossbreeding.

Differential diagnosis

1. Iridescent sympathetic damage caused by sympathetic damage can decolorize the iris, which has been confirmed by animal experiments. Clinically, such as Horner syndrome, Parry-Romberg syndrome. In addition to the signs of iridescent ciliary body inflammation, Horner syndrome has signs of ptosis, eyeball retraction, dilated pupils, no sweat on the side of the skin, and causes of sympathetic damage. (trauma, surgery, Pancoast mass, aortic aneurysm, internal carotid artery thrombosis, etc.), generally easy to discriminate; Parry-Romberg syndrome is rare, also monocular, eye lesions are basically the same as HI except KP, from the affected side The presence or absence of muscle progressive atrophy was identified.

2. Simple iris heterochromia is abnormal for iris development, no inflammation, and more eyes.

3. Other causes of diffuse iris atrophy caused by chronic iridocyclitis can be seen in pigment KP, anterior lens pigmentation, and post-iris adhesion.

4. HI with secondary glaucoma should be differentiated from glaucomatocyclitic crises syndrome. Both of them belong to secondary open angle glaucoma, but the latter KP is round, large, and triangular in the posterior cornea. There is no filament-like relationship between KP, and the iris has no color. The iris of the two eyes is very rare in humans. Usually this is an indicator of eye disease, such as chronic iritis or diffuse iris melanoma, but it may also be a normal variant. Iridescent color is common in some specific dog and cat breeds, such as Siberian ferrets, Australian Shepherd dogs, Border Collies, and White Persian cats, mainly due to crossbreeding.

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