Eosinophilic granuloma formation in the liver

Introduction Paragonimus in Sichuan often invades the liver and forms eosinophilic granuloma in the liver. Pulmonary paragonimiasis, its clinical manifestations are also diverse. The incubation period is several days to 20 years, most of them within one year. According to the main organs invaded by it, it can be divided into 4 types clinically. The disease can be obtained in the endemic areas or in the epidemic areas, through the contamination of raw or semi-raw stone crabs, oysters, marsh shrimp, red maiden or drinking water and utensils (knives, chopping boards). The key to preventing this disease is to prevent stone crabs, cockroaches and raw water that are not raw or half-baked, to prevent infection, to spit, to not urinate, and to prevent eggs from rushing into the stream with rainwater. Once the patient is ill, he should be treated thoroughly.

Cause

Causes:

A disease caused by parasites. Paragonimiasis is a parasitic disease of humans and animals. It has three hosts in its lifetime: the freshwater snail is its first intermediate host, the host of parasitic cercariae, and the river crab is its second intermediate host. After the crab body, the capsule is formed. It can also be parasitic to tissues or organs other than the lungs. The eggs are mainly coughed up with the cockroaches and later hatched into the edulis in the water. The edulis invade the first intermediate host, the freshwater snail, through the cellulase, thunder and other developmental stages and finally become the scorpion. The cercaria enters the second intermediate host, and the body of the freshwater stone crab or pupa develops into a sac. If a person eats a raw or uncooked stone crab or cockroach containing such a sac, the sac will enter the digestive tract and become a child worm by the digestive juice. The activity of the larvae is very strong, and the function of the secreted enzyme can pass through the intestinal wall to the surface of the peritoneal serosa. Most of the larvae move up the liver surface and directly penetrate the sac to the chest cavity, thereby invading the lungs. And develop into adults.

A small number of child worms stay in the abdominal cavity, continue to develop, and penetrate into the shallow layer of the liver or the omentum to become an adult. Occasionally, the soft tissue around the root of the large vessel and the internal carotid artery can move upward along the mediastinum, invade the concave cavity through the ruptured hole, and invade the brain tissue through the bottom of the temporal lobe and occipital lobe. After the insect invades the organ or tissue, in addition to causing the lesion, it can continue to travel to other parts to cause the lesion. Generally, it takes about 2 to 3 months to enter the body from the cystic sac to mature in the lungs. The insect can generally live for 5 to 6 years in the host.

an examination

Related inspection

Liver function test liver ultrasound liver palpation abdominal fluoroscopy liver and gallbladder percussion

1, according to epidemiological data, especially in the epidemic areas and have the opportunity to swallow live cystic, with the above clinical manifestations, chest X-ray signs, eosinophils increased, should be considered for diagnosis.

2, sputum, feces, subcutaneous nodules biopsy to find eggs or worms can be diagnosed.

3. Immunological examination has diagnostic significance for those with negative pathogen tests.

Differential diagnosis

Identification:

Due to the complex clinical manifestations of Paragonimus dylinae, it is easily misdiagnosed. Should be noted with tuberculosis, lung cancer, tuberculous pleurisy, peritonitis, brain tumors and other identification.

diagnosis:

According to epidemiological data, especially in the epidemic areas and have the opportunity to swallow live cysts, the above clinical manifestations, chest X-ray signs, eosinophils, should be considered for diagnosis. Biopsy of sputum, feces, and subcutaneous nodules can be diagnosed by finding eggs or worms. Immunological examination has diagnostic significance for those with negative pathogen tests.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.