Fever with bleeding

Introduction Fever with bleeding refers to the disease that causes the body's pathological temperature to rise with symptoms of bleeding. Common in severe infections and blood diseases. The former such as severe measles, epidemic hemorrhagic fever, dengue fever, viral hepatitis, typhus, sepsis, infective endocarditis, leptospirosis. The latter are acute leukemia, acute aplastic anemia, malignant histiocytosis. In recent years, the application of serological methods has been helpful for early diagnosis of patients, especially for patients with clinical atypical symptoms.

Cause

Common in severe infections and blood diseases. The former such as severe measles, epidemic hemorrhagic fever, dengue fever, viral hepatitis, typhus, sepsis, infective endocarditis, leptospirosis. The latter are acute leukemia, acute aplastic anemia, malignant histiocytosis.

an examination

Related inspection

Regression of the thermospin (BR) Hepatitis A virus antigen (HAVAg) Sarcoidosis antigen (Kveim) test neutrophil ratio (NEUT%) histamine challenge test

Symptoms: fever with bleeding

1. General laboratory examination: the total number of blood leukocytes increased, lymphocytes increased in the classification, and abnormal lymphocytes, the number of platelets decreased. Urine tests include protein, red blood cells, white blood cells, and casts.

2. Specific experimental diagnosis: The application of serological test in recent years is helpful for early diagnosis of patients, especially for patients with clinical atypical. The detection methods include indirect immunofluorescence test, enzyme-linked immunosorbent assay, enzyme-labeled SPA histochemistry test, hemagglutination inhibition test, immunoadhesive blood coagulation test, solid phase immunoglobulin adsorption test and solid phase radioimmunoassay. Specific IgM-positive or serum-specific IgG antibody titers increased more than 4 times in the early stage of the onset and in the recovery period, and all have diagnostic value. The isolation of the virus from the patient's blood or urine or the detection of viral antigens can also be diagnosed. The use of polymerase chain reaction (PCR) to directly detect viral antigens is helpful for pathogen diagnosis.

Differential diagnosis

(1) fever with lymphadenopathy, accompanied by tenderness

May be caused by a local infection. Such as systemic lymphadenopathy, suggesting that there may be lymph node tuberculosis, leukemia, lymphoma, metastatic cancer.

(2) fever with joint swelling and pain

Can be seen in sepsis, scarlet fever, brucellosis, tuberculosis, rheumatic fever, connective tissue disease, gout and so on.

(3) fever accompanied by rash

Common in rash infections. Such as measles, scarlet fever, etc.

(4) fever with cough, sputum, chest pain

Common in respiratory diseases.

(5) fever accompanied by abdominal pain, diarrhea, nausea, vomiting

Common in digestive disorders.

(6) fever accompanied by frequent urination, urgency, dysuria, and back pain are common in urinary tract infections. As mentioned above, there are many causes of fever, both physiological and pathological. Patients should not mistakenly believe that fever is caused by infection and abuse of antibiotics and antipyretics.

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