Extensive thymectomy

A surgical treatment for patients with myasthenia gravis by removing the thymus. The thymus is the central target organ and plays an important role in the pathogenesis of myasthenia gravis. Various pathogenic factors such as anti-acetylcholine receptor antibodies in the blood, complement C3, killer T cells and lymphokines, and most of the helper T cells in the thymus Initiating antigens (ie, muscle-like cells) that are internally synthesized or sensitized in the thymus and cause an autoimmune response to myasthenia gravis are also present in the thymus. Extensive thymectomy is a surgical procedure for the treatment of myasthenia gravis. Treatment of diseases: myasthenia gravis Indication Thymoma with or without myasthenia gravis, thymic hyperplasia with myasthenia gravis. Contraindications 1, with systemic diseases, can not tolerate surgery. 2, local infection, not suitable for surgery. Preoperative preparation 1. Control lung infections. 2. For patients with myasthenia gravis, an effective therapeutic dose of anticholinesterase should be developed. Surgical procedure 1. Incision: The median incision of the sternum. 2. After pushing the pleura back to the sides, you can see the thymus tissue in the anterior mediastinum. 3. Lift the lower pole of the thymoma, and carefully separate the adipose tissue from the bottom to the top and cut it off. 4. Stainless steel wire sutured the sternum. The drainage tube is placed behind the sternum. The incision was sutured layer by layer. complication Postoperative infection.

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