Paravaccinia

Introduction to the vaccinia MilkersNode, also known as vaccinia, is a viral skin disease caused by exposure to a fake vaccinia virus when a milkman is milking. basic knowledge The proportion of sickness: the incidence of milkers is about 2-5% Susceptible people: no special people Mode of infection: non-infectious Complications: urticaria

Cause of vaccinia

It is caused by the pox virus of the cow's breast. Under the electron microscope, the virus has a cylindrical shape with a protruding end and the core is a dense DNA. This virus can grow and grow in the tissue culture of bovine cells, but it is different from the vaccinia virus. Can not grow in the tissue cells of monkeys or humans.

Vaccination against vaccinia

1. Workers often occur in milking or slaughterhouses.

2. Caused by a false vaccinia virus infection.

3. Often occurs in the hands, forearms and other parts.

4. Dark red papules develop into soft, non- tender nodules, central depression, single or several lesions.

5. Often through six stages: plaque stage, target stage, acute exudation, nodule stage, papillary stage and regression stage.

6. Can naturally fade.

Paraxillary complications Complications urticaria

The main complication was secondary infection after nodule rupture.

Symptoms of vaccinia Common symptoms Red pustules polymorphous erythematous rash pimples

The incubation period is 5 to 14 days. It begins with a single or several inflammatory papules on the forearm. It turns into a purple-red hemispherical nodule. It has a red halo around it. The center is umbilical. The texture is tough, the size of the soybean is smooth, and the surface is smooth. The scattered distribution does not fuse with each other, sometimes there is a blisters or pustules on the top, and later scarred, or gradually develop, becoming papillary pale red skin lesions, similar to purulent granuloma, after about 6 weeks, the skin lesions naturally subsided, no Traces, mild systemic symptoms, sometimes accompanied by local lymphadenopathy, some patients, within 1 to 2 weeks of nodules, in the hands, forearms, upper limbs, lower limbs and neck, etc., papules, herpes, sputum Measles and polymorphic erythematous rash, a toxic or allergic reaction that resolves within 1 to 2 weeks.

Inspection of vaccinia

Histopathology: epidermal hyperplasia and pseudoepithelial neoplasia, multiple atrial blister can be seen in the sinus, in the cytoplasm, occasionally virus inclusion bodies can be found in the nucleus, granuloma reaction can occur in the upper part of the dermis.

Diagnostic identification of vaccinia

diagnosis

According to the occupational medical history and the clinical characteristics of the epidemic history of dairy cows, it is not difficult to diagnose. If there are conditions for electron microscopic observation of biopsy or suede, virus inclusion bodies can be found, which is more helpful for the diagnosis of this disease.

Differential diagnosis

Clinically, it needs to be differentiated from infectious soft palate and suppurative granuloma.

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