Major Syndrome

Introduction to Major Syndrome Major Syndrome is a group of extrapyramidal disorders first described by French neurologist Henry Meige. Mainly manifested as binocular palpebral, temporomandibular dystonia, facial muscle tone disorder-like involuntary movement. Henry Meigee first reported Major Syndrome in 1910. Since then, it has been called Brueghel syndrome, eyelids, and temporomandibular dystonia. basic knowledge The proportion of illness: 0.002% Susceptible people: middle-aged women Mode of infection: non-infectious Complications: difficulty swallowing muscle atrophy

Cause of Meyer Syndrome

According to the analysis of American data, the age of onset of hereditary idiopathic dystonia is 4 to 16 years old (mean 10.4 years). Incidence: According to the analysis of American flow data, the incidence of hereditary idiopathic dystonia For a population of 1/40000, the carrier is about 1/200 of the population.

Major Syndrome Prevention

Pay attention to rest and avoid overwork.

Meyer Syndrome Complications Complications, difficulty swallowing, muscle atrophy

(1) radiculopathy: due to the lesions of the collateral nerve roots of the spinal cord, it can lead to muscle atrophy caused by muscle denervation, and abnormalities such as numbness and acupuncture.

(2) Muscle pseudohypertrophy: a type of muscular dystrophy. Muscular dystrophy is mainly caused by genetic factors, and in addition to genetic factors, the patient's own genetic mutation can also cause the disease. Clinically, progressive muscle atrophy is the main clinical manifestation.

(3) difficulty in swallowing: because the lesion can affect the muscles of the epiglottis, it can cause difficulty in swallowing.

Symiosis symptoms common symptoms eyelid drooping photophobia difficulty dyspnea dyspnea

This disease is more common in older women, with both eyes as the first symptom, and sag and sputum weakness are also common. Part of the onset of a single eye, gradually with both eyes. The remaining first symptoms were increased frequency of blinks, mental illness, dental problems, and dystonia in other areas (mainly in the cranial neck). Healing improves when he sleeps, speaks, sings, yawns, and opens his mouth. It can be induced or aggravated by strong light, fatigue, nervousness, walking, watching, reading, and watching TV.

Examination of Major Syndrome

Blood electrolytes, drugs, trace elements and biochemical tests help to diagnose and classify the cause.

1. CT or MRI examination: It is meaningful for differential diagnosis.

2. Positron emission tomography (PET) or single photon emission tomography (SPECT): It can show some biochemical metabolism in the brain, which is meaningful for diagnosis.

3. Genetic analysis: It is important to diagnose certain hereditary dystonia diseases.

Diagnosis and diagnosis of Meijie syndrome

Attention is distinguished from myoclonus, snoring, etc. The muscle tension of this disease is a centrally intense involuntary muscle contraction, which is different from Parkinson's disease.

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