Mycoplasma infection in pregnancy

Introduction to pregnancy with mycoplasma infection Mycoplasma infection during pregnancy can lead to serious complications such as late abortion, premature birth or stillbirth. Mycoplasma is the smallest microorganism that can survive independently without a cell wall between bacteria and viruses. There are about 12-14 species of mycoplasma infecting humans, among which human mycoplasma and Ureaplasma urealyticum are most common in female genital tract. MH infection causes vaginitis, cervicitis and salpingitis, while UU causes non-gonococcal urethritis. Mycoplasma coexists with the host, does not show symptoms of infection, can only cause opportunistic infection under certain conditions, and often combined with other pathogens to cause disease. Recently, it has been found that Mycoplasma pneumoniae (MP), Mycoplasma genitalium (MG), etc. can also cause infection in mother and child. basic knowledge The proportion of illness: 0.002%-0.005% Susceptible population: pregnant women Mode of transmission: sexual transmission, contact, transmission, vertical transmission Complications: Premature delivery Mycoplasma pneumonia Chronic pneumonia Pelvic inflammatory disease Neonatal pneumonia

Pregnancy with mycoplasma infection

1. Direct transmission, that is, sexual communication, is the main way to spread UU and CT.

2. Indirect transmission of UU and CT can be spread by touching items contaminated by patient secretions, such as bath water and shared towels. Less common in adults.

3, the transmission of fetal and neonatal UU and CT can be through the intrauterine, birth canal and postpartum infection, the main way of infection through the birth canal.

Pregnancy with mycoplasma infection prevention

1, active exercise on a regular basis to exercise regularly, sleep indoors to keep the air fresh, the temperature is suitable for children should open the window to sleep, at least indirect ventilation. Make the most of the sunbathing air bath and water bath. Enhancing physical fitness is the first important factor in disease prevention.

2, talk about hygiene to avoid cross-infection. Not to crowded, poorly ventilated theater department stores, supermarkets, etc. Try to avoid contact with patients who are close to the doctor, run a large hospital, and shorten the waiting time. In the past, respiratory diseases were only transmitted by breathing. In recent years, it has been confirmed that exposure to infection is an important mode of transmission. It should be noted that it is not to let children passively smoke. Being smoked is an important reason for increasing respiratory diseases in children.

3, drug prevention Some Chinese and Western medicine can improve the body's cellular and humoral immune function, preferably under the guidance of a doctor. Vaccination Vaccines are currently used in some places, but they are not yet widely available. Vaccines have been designed for prevention but the protection rate is only 50%, and there is no systematic report on antibiotic prophylaxis.

Pregnancy with complications of mycoplasma infection Complications premature mycoplasmal pneumonia chronic pneumonia pelvic inflammatory disease neonatal pneumonia

1. UU and MH can cause chorioamnionitis in the placenta of amnion injury during the first 16-20 weeks of pregnancy, leading to late abortion, premature birth or stillbirth.

2, neonatal, especially premature infants can develop mycoplasmal pneumonia and chronic pneumonia after UU infection.

3, MH can lead to postpartum pelvic inflammatory disease and postpartum mycoplasmosis and neonatal mycoplasma.

4, postpartum lactation and other contact or air infection with MP caused by neonatal pneumonia.

Pregnancy with symptoms of mycoplasma infection Common symptoms Increased vaginal discharge in pregnant women with abdominal pain

UU and CT infections are asymptomatic, mild or unspecific.

1 Cervical mucositis, UU infection is more asymptomatic, CT infection, 70% to 90% without clinical symptoms. If the symptoms are manifested as increased vaginal discharge, mucopurulent, bleeding after sexual intercourse.

2 endometritis, manifested as lower abdominal pain, increased vaginal discharge, irregular bleeding in the vagina.

3 Fallopian tube inflammation is characterized by long-term mild lower abdominal pain, low fever, long-term unhealed, can be manifested as extensive pelvic adhesions.

Examination of pregnancy with mycoplasma infection

1. Mycoplasma culture: combined with vaginal and urethral secretions, a higher positive rate can be obtained.

2, serological examination: serum levels of MH and UU serum-specific antibodies in asymptomatic women are low, serum antibodies can be significantly increased after re-infection.

3, neonatal specific IgM elevation has a certain predictive effect on mycoplasma infection, but failed to become a routine detection method.

4, PCR detection: more sensitive and specific than the culture method, has a reference value for clinical diagnosis.

Diagnosis and diagnosis of pregnancy complicated with mycoplasma infection

diagnosis

According to the clinical manifestations, the examination can be diagnosed.

Differential diagnosis

When mycoplasma is combined with other pathogens, it mainly manifests as non-gonococcal urethritis and other inflammation of the reproductive tract. The identification of the disease mainly depends on laboratory testing. 1 original culture: more vaginal and urethral secretions combined culture, can get a higher positive rate. 2 Serological examination: serum and MH and UU serum-specific antibody levels were low in asymptomatic women, and serum antibodies were significantly increased after re-infection. Neonatal specific IgM elevation has a predictive effect on mycoplasma infection. However, they have not become routine testing methods. 3PCR detection: It is more sensitive, specific and rapid than the culture method, and has reference value for clinical diagnosis.

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