Vitreous liquefaction

Introduction to vitreous liquefaction The vitreous is the content located in the posterior segment of the eyeball. Normally a transparent gel state. 99% of them are water, and a small amount of collagen, hyaluronic acid and the like. The vitreous has an important refractive function and supports the eyeball. In the pathological condition, the vitreous gel state is destroyed and becomes a liquid. This condition is medically referred to as vitreous liquefaction, a degeneration process of the vitreous. Usually occurs after the age of 60, starting from the central part of the vitreous, a small liquefaction chamber appears, and the liquefaction range is continuously expanded. It is due to metabolic changes in the vitreous body, or oxidation of vitamin C, oxygen and iron ions in the vitreous glass, causing hyaluronic acid macromolecule degradation, collagen fiber scaffold collapse and concentration, water analysis, gel denaturation and becoming a liquid, This condition is medically referred to as vitreous liquefaction, a degeneration process of the vitreous. basic knowledge The proportion of illness: 0.003% Susceptible people: no specific people Mode of infection: non-infectious Complications: macular hole

Vitreous liquefaction cause

Abnormal vitreous metabolism (30%):

It is due to metabolic changes in the vitreous body, or oxidation of vitamin C, oxygen and iron ions in the vitreous glass, causing hyaluronic acid macromolecule degradation, collagen fiber scaffold collapse and concentration, water analysis, gel denaturation and becoming a liquid, This condition is medically referred to as vitreous liquefaction, a degeneration process of the vitreous. At the same time, due to the aggregation of solid components, or the intrusion of blood and other constituents, the transparency of the vitreous body changes, and an opaque body appears, which is called opacity of the vitreous. At this time, a bit of a shape or a filamentous black shadow flutters. Vitreous opacity is not a simple disease, it can be caused by a variety of diseases.

Vitreous opacity (20%):

A variety of eye diseases can cause vitreous opacity, the most common are senile degeneration, myopia changes, posterior vitreous detachment and physiological floaters, in addition to retinal detachment, uveitis, primary familial amyloidosis, vitreous vitreous Liquefaction, etc. can also occur in the clinical manifestations of the front of the shadow. Here are a few common diseases that can cause vitreous opacity. Senile degeneration elderly vitreous degeneration caused by mosquitoes is characterized by insidious onset, mild symptoms and small changes. Although the patient has a phenomenon of flying mosquitoes, in addition to vitreous liquefaction on the objective examination, the turbidity point in the vitreous body is often not found. It is a harmless vitreous opacity with no serious consequences, does not affect vision, and does not require treatment.

Vitreous liquefaction prevention

Vitreous liquefaction often has vitreous detachment, but without vitreous retinal adhesion or cord traction, it will not cause serious visual impairment. This disease does not require special treatment, just pay attention to prevent the development of myopia. In the operation of intraocular surgery, the vitreous body is prevented from coming off and the lens is dislocated due to the fragility of the lens suspensory ligament.

Vitreous liquefaction complications Complications

The vitreous and retina are closely related, and the lesions of the two often affect each other. Liquefaction of the vitreous will cause the vitreous to form a cavity. As the liquefied cavity expands, the liquefied vitreous enters the retina through the slit of the posterior vitreous membrane. The retina is separated from the vitreous, and the patient may have a flying mosquito, a flickering sensation, or a loss of vision. Severe vitreous liquefaction can cause the retina to cause retinal tears or macular holes, leading to severe vision loss or even blindness.

Symptoms of vitreous liquefaction Common symptoms Repeated infection with diffuse bleeding of myopia

Under the slit lamp, there is an optical gap in the vitreous cavity, and there is a little white turbidity or a floating film in the vicinity. The incidence of vitreous liquefaction increases with age and axial length. Aphakic eyes, inflammation, trauma, myopia, bleeding, etc., are also associated with vitreous liquefaction.

Vitreous liquefaction check

When doctors perform eye examinations on such patients, they need special dilated examinations. It can be found that in the ophthalmoscopy, the black or semi-transparent points are visible when the patient's eyes are rotated up and down and left and right. Shape, strip, block turbidity fluttering. Primary lesions can be seen on the fundus of the patient, such as inflammatory exudates, red bleeding, and white degeneration. Therefore, if necessary, it is necessary to perform eye ultrasound and electrophysiological examination on the patient to help understand the nature of vitreous opacity and the condition of the retina.

Diagnosis of vitreous liquefaction

diagnosis

Some vitreous opacity is due to pathological causes, which can be a complication or development of many endoscopic lesions. This kind of vitreous opacity is common in the eye inflammation, which is one of the more common causes, mainly iridocyclitis, uveitis, retinitis, etc.; vitreous, retinal hemorrhage, lightly only flaky turbidity, heavy Can make the pupil area dark, more common in patients with diabetes and hypertension, retinal detachment, vitreous opacity is often the main manifestation of the early stage of this disease, and gradually increase the shadow with the fixation before the eye, affecting vision, eye trauma, can be worn through the injury Caused by bleeding or infection, systemic diseases such as nephritis, gestational poisoning, parasitic diseases including intravitreal parasites.

Differential diagnosis

Different from other eye diseases.

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