Pasini-Pierni progressive skin atrophy

Pasini-Pierni Introduction to Progressive Skin Atrophy Pasini-Pierni progressive idiopathic skin atrophy (progressiveidiopathicatrophyofPasiniandPierni), since Pasini-Pierni reported this disease in 1923, there is limited superficial atrophic scleroderma (atrophosclerma superficialiscircumscripta), diffuse idiopathic skin atrophy (atrophiacutisidiopathicadiffusa ) and so on. It is a special type of pigmented skin atrophy. There is an atrophic subtype that is thought to be a localized scleroderma. basic knowledge The proportion of illness: 0.018% Susceptible people: more than adolescents, more men than women Mode of infection: non-infectious Complications: keloids

Pasini-Pierni progressive skin atrophy

(1) Causes of the disease

Still not clear. Although patients with the same symptoms are found in the family, there is no genetic evidence. Surgery, blood loss, and infection may be predisposing factors.

(two) pathogenesis

The pathogenesis is still unclear. May be related to surgery, blood loss, infection.

Pasini-Pierni progressive skin atrophy prevention

Beneficial foods: Tianji oil, sand worms, ferrets, pig skin, armor and other tonic products, milk, fish, eggs, lean meat, soy products and other protein-rich foods.

Unhelpful food: cold food such as mung bean, kelp, melon, watermelon, smoke, wine, strong tea, espresso and other spicy and irritating foods.

Comprehensive dietary control of dietary fat intake, some experts suggest that the energy provided by fat should not exceed 7-10% per day, increase the content of vegetables, fruits and cereals in the diet.

Pasini-Pierni progressive skin atrophy complications Complications keloid

Sometimes the damage is similar to the shrinkage of the hard spot disease, but there is no hardening change. The development is slow and benign, and it naturally stops growing after months or years.

Pasini-Pierni progressive skin atrophy symptoms common symptoms skin lesions like dry stucco-like lip or oval erythema hard spot sclerosis

The initial skin lesions are pale erythema, slightly swollen, and later become slate gray or cyan gray round, oval or irregularly shaped smooth atrophic patches, slightly concave, clear boundaries, single or multiple irregularities, The size can range from a few centimeters to more than 10 cm. Sometimes the damage is similar to the shrinkage of the hard spot disease, but there is no hardening change. The development is slow, and after being benign, it usually stops growing after several months or years. More common in teenagers, more men than women. The site of the disease is mainly found in the trunk, and occasionally can occur in the proximal extremities, generally no symptoms.

Pasini-Pierni examination of progressive skin atrophy

Histopathology: In addition to thickening of collagen fiber bundles and chronic inflammatory infiltration in the early stage, there is often no special change. Old damage, inflammatory infiltration is not obvious, but the deep collagen band of the dermis becomes thicker and the density increases, showing uniform homogenization and degeneration. The epidermis is atrophied and there is no special change in the subcutaneous layer.

Pasini-Pierni diagnosis of progressive skin atrophy

diagnosis

According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.

Differential diagnosis

1. Hard spot disease resembles ivory white hardened plaque, surrounded by edematous lavender halo, first with sclerosing edema, followed by atrophy, histopathology for hardening without atrophy.

2. The plaque atrophy is a pale white flat bulge, or a slight depression atrophy, and the finger pressure has a feeling of embedding.

3. Subcutaneous fat atrophy is characterized by reduced or lack of subcutaneous fat, and the skin color is normal.

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