Palmoplantar fibromatosis

Introduction to palmoplantar fibromatosis Palmar implant disease (palmarandplantarfibromatosis) includes both palmar fibrosis and ankle fibrosis, both of which are similar in terms of histopathology, infiltration, and recurrence after resection. However, it is rare for both diseases to occur at the same time. basic knowledge The proportion of illness: 0.001% Susceptible people: no specific population Mode of infection: non-infectious Complications: cirrhosis, diabetes, epilepsy

The cause of palmotencular fibrosis

(1) Causes of the disease

The etiology of this disease is not clear, and may have certain correlation with environmental factors, genetic factors, dietary factors, and mood and nutrition during pregnancy.

(two) pathogenesis

The pathogenesis is still unclear. The tissue biopsy tumor cells are fusiform, have wavy nuclei, and are arranged in an interlaced bundle in the corrugated collagen matrix. In the early stage, there were many cellular components, and the late cellular components were significantly reduced.

Palmar fibrosis prevention

The etiology of this disease is not clear, and may have certain correlation with environmental factors, genetic factors, dietary factors, and mood and nutrition during pregnancy. Therefore, it is impossible to directly prevent the primary disease. Early detection, early diagnosis, and early treatment are important for preventing this disease. For patients with a family history, a chromosomal examination should be performed before marriage to prevent the disease from being passed on to future generations.

Palmoplantar fibrosis complications Complications cirrhosis diabetes epilepsy

This disease is often caused by skin rupture and the integrity of the skin is destroyed. Because the skin integrity is destroyed, it can cause skin bacterial infection or fungal infection due to scratching, usually secondary to low body constitution, or long-term use of immunosuppressants and ash. Children with fungal infections such as nails, such as concurrent bacterial infections, may have fever, skin swelling, ulceration, and purulent secretion. Severe cases can lead to sepsis, which should be brought to the attention of clinicians. At the same time, because the tumor compresses the blood vessels, it causes numbness, pain, and foreign body sensation.

Symptoms of palmofibromatosis common symptoms nodular fungal infections ankle fibrosis

1. palmar fidromatosis (palmar fidromatosis), also known as Dupuytren contracture, fibrosis of the palmar aponeurosis, often in the middle-aged male 30 to 50 years old, the damage is multiple solid nodules in the palm, usually It is 3 to 5, and the diameter of 1 scene cm occurs at the proximal end of the 4th finger. Later, the function of flexion and contracture is impaired. This disease is sometimes associated with alcoholic cirrhosis, diabetes and chronic epilepsy, and Peyronie disease. , ankle fibrosis and knuckle pad accompanied.

2. Plantar fibromatosis (also known as Ledderhose disease) is a similar disease of the crotch of the palmar fibroid disease. The axillary part of the crotch is slowly enlarged, causing difficulty in walking or even holding.

Examination of palmotencular fibromatosis

Histopathology: The tumor cells are fusiform, with wavy nuclei, arranged in a corrugated collagen matrix in an interlaced bundle, with many early cellular components and a significant decrease in late cellular components.

Clinical skin examination: The lesion is multiple solid nodules in the palm, usually 3 to 5, with a diameter of 1 cm, occurring at the proximal end of the 4th finger, resulting in impaired function of flexion and contracture.

Diagnosis and differentiation of palmoplantar fibromatosis

According to the clinical manifestations of this disease, it should be differentiated from skin tuberculosis. Skin tuberculosis, also known as liquefied skin tuberculosis or skin adenosis, is one of the common skin tuberculosis diseases caused by Mycobacterium tuberculosis. Tuberculosis is often accompanied by other tissues or organs, of which lymph node tuberculosis, bone and joint tuberculosis are most common. Occurs in the neck, underarms, upper chest, groin and so on. Primary spastic skin tuberculosis, also known as tuberculous gumma, is caused by blood-borne dissemination. The nodules are often located in the extremities and are not connected to glands, bones or other tissues. However, this disease occurs mostly in children or youth, especially in young women. According to the history of the disease, it can be clearly identified.

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