Juvenile hyaline fibromatosis

Introduction to juvenile hypolitic fibroma Juvenile hyalinar fibrosis (juvenilehyalincfibromatosis) is a rare and unexplained disease with autosomal recessive genetic disease, which may be associated with mental retardation, gingival hyperplasia, flexion contracture and bone damage. basic knowledge The proportion of illness: the incidence rate is about 0.002%-0.005% Susceptible people: no special people Mode of infection: non-infectious Complications: mental retardation

The cause of juvenile hypolitic fibroma

(1) Causes of the disease

The cause is still unknown. It depends on the actual condition of the patient.

(two) pathogenesis

The pathogenesis is still unclear.

Juvenile hyaluromatosis prevention

There is no effective preventive measure for this disease. Early detection and early diagnosis are the key to the prevention and treatment of this disease.

Juvenile hyaline fibroma complications Complications, mental retardation

Congenital anomalies such as mental retardation, gingival hyperplasia, flexion contracture and bone damage may be associated. At the same time, it is also possible to combine the dysplasia of other tissues and organs, and the morphology and dysfunction of tissues and organs.

Symptoms of juvenile hyaline fibroma Symptoms Toe flexure contracture papules nodular hyperplasia hyperactivity

Skin lesions are multiple papules of several millimeters in size, to large nodules or masses of several centimeters in diameter, which occur in the head, neck and upper torso. Children who are first born before the age of 5 grow slowly and new damage can continue to occur. In adulthood, there are generally no symptoms.

Examination of juvenile hypolitic fibromatosis

Histopathology: nodules consist of a small number of cells and stroma, new small tumor cells are more, and larger tumors contain more matrix. In formalin-fixed specimens, fibroblasts are artificially contracted. The gap is formed to make the cells have an ointment-like appearance, the matrix is glass-like homogeneous eosinophilic, similar to a transparent substance, PAS staining is strongly positive reaction, and resistant to amylase.

Diagnosis and diagnosis of juvenile hyaline fibroma

According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.

Generally not confused with other diseases.

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