Zieve syndrome

Introduction to Zieve Syndrome Zieve syndrome is also known as alcoholic hyperlipidemia syndrome, jaundice transient hyperlipidemia - hemolytic anemia syndrome, alcoholism hyperlipidemia hemolysis syndrome. The disease is caused by alcoholic damage caused by liver damage and different degrees of cholestasis, which causes jaundice. Alcohol can cause an increase in plasma free fatty acids, and due to increased intrahepatic lipid formation, serum triglycerides increase, and hyperlipidemia leads to erythrocyte membrane. Changes in lipid composition, membrane dysfunction, increased fragility leading to hemolysis, in addition, pancreatitis caused by alcoholism and vitamin E deficiency, also associated with hemolysis. basic knowledge The proportion of illness: 0.001% Susceptible people: long-term drinkers, more men than women Mode of infection: non-infectious Complications: cirrhosis, ascites, spider mites, nystagmus,

Causes of Zieve syndrome

The disease is caused by alcoholic damage caused by liver damage and different degrees of cholestasis, which causes jaundice. Alcohol can cause an increase in plasma free fatty acids, and due to increased intrahepatic lipid formation, serum triglycerides increase, and hyperlipidemia leads to erythrocyte membrane. Changes in lipid composition, membrane dysfunction, increased fragility leading to hemolysis, in addition, pancreatitis caused by alcoholism and vitamin E deficiency, also associated with hemolysis.

Zieve syndrome prevention

Preventive measures: Alcohol withdrawal can fundamentally prevent the occurrence of this disease.

Zieve syndrome complications Complications cirrhosis ascites spider eyeball tremor

In the advanced stage, there may be cirrhosis such as ascites, liver palm spider mites, etc., after stopping drinking, there may be tremors and convulsions.

Symptoms of Zieve Syndrome Common Symptoms Liver enlargement, protein, urine, ascites, dyslipidemia, nausea and hardening

1. More common in patients with long-term drinking history and chronic alcoholism, often after vomiting, nausea and vomiting, anorexia and upper abdominal pain.

2. The liver is swollen, the texture is moderate and tender, and there are few splenomegaly. In the advanced stage, there may be cirrhosis, such as ascites, liver palm, spider mites, etc., after stopping drinking, there may be tremors and convulsions. Scleral yellow staining.

3. Hemoglobinuria and hemorrhagic anemia such as hemosiderin.

Inspection of Zieve syndrome

1. Blood: Hemoglobin is reduced, reticulocytes are increased, and red blood cell morphology is changed, such as red blood cells, spherical red blood cells, target cells, and the like.

2. Increased erythrocyte fragility.

3. Bone marrow examination is active in the red blood cell system.

4. Increased blood lipids, including cholesterol, phospholipids and triglycerides.

5. Increased serum bilirubin, increased alkaline phosphatase, and abnormal liver function.

6. Liver biopsy has changes in fat infiltration and cirrhosis.

Diagnostic identification of Zieve syndrome

Generally diagnosed by a systemic examination.

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