Lip and tongue edema and facial paralysis syndrome

Introduction of lip edema and facial paralysis syndrome Lip edema and facial paralysis syndrome, also known as Melkersson-Rosenthel syndrome, has a rapid onset, swollen tongue and swelling of the lateral tendon, often showing tongue swelling or deep longitudinal fissure tongue, the syndrome of this syndrome Characteristic performance. This syndrome was first described by Melkersson (1928), after which Rosenthel (1930) found that in addition to face, lip swelling and facial paralysis, there is still a longitudinal longitudinal fissure, like scrotal skin wrinkles. basic knowledge The proportion of illness: 0.0013% Susceptible people: no specific people Mode of infection: non-infectious Complications:

Lip and mouth edema and the cause of facial paralysis syndrome

(1) Causes of the disease

The cause is still unknown, and it is speculated that it may be related to genetic factors. It is also reported that the disease is caused by certain pathogen infections and is thought to be related to immune factors; it is generally believed that peripheral facial paralysis is caused by edema affecting the facial nerve canal.

(two) pathogenesis

The pathogenesis of the disease is unknown. According to the literature, the possible factors are:

1. Some patients have familial morbidity, presumably related to genetic factors, and there are reports of autosomal dominant inheritance with different expression patterns.

2. According to Kesler et al., the pathological examination of the swollen lip tissue confirmed non-specific acanthosis and chronic inflammation of the subepithelial, which is a granulomatous nature. It is suspected that the disease is caused by infection of certain pathogens.

3. Because the condition is episode, some scholars believe that it is related to immune factors.

4. There are also reports of neurovascular edema caused by mechanical stimulation.

5. Face gods are often involved, it is generally believed that the lingual edema of the tongue is spread to the facial nerve tube, so that the facial nerve is compressed, and peripheral facial paralysis occurs.

Lip and mouth edema and facial paralysis syndrome prevention

Early comprehensive treatment, to reduce complications, genetic counseling for family factors, preventive measures include avoiding close relatives marriage, carrier genetic testing.

Lip and mouth edema and complications of facial paralysis syndrome Complications

May be accompanied by loss of taste and hearing allergies.

Lip and tongue edema and facial paralysis syndrome symptoms common symptoms hearing allergies paralysis taste loss

1. More incidence in adolescents, no gender differences, rapid onset, often beginning with swelling of the lips, sometimes spread to the cheeks, scalp, no conscious pain, swelling of the lateral tendon, sometimes accompanied by loss of taste and hearing hypersensitivity, the above clinical manifestations Generally lasting for several days, the swelling of the face tongue can naturally subside, and the peripheral facial paralysis will gradually improve, but the longitudinal fissure of the tongue will still exist. The symptoms can reappear after several weeks and several months, but the lesion side is uncertain when recurring.

2. In addition to peripheral facial paralysis and swelling of the lips, it is often seen that the tongue is swollen or has a deep longitudinal fissure of the tongue. This lingual fissure is a characteristic manifestation of the syndrome.

Examination of lip edema and facial paralysis syndrome

1. The routine examination of blood and cerebrospinal fluid is non-specific, and the blood picture may be slightly higher at the onset.

2. Check blood sugar, biochemical and immune items. If abnormal, it has differential diagnosis.

3. Genetic testing may have diagnostic value.

If the following items are abnormal, there is a differential diagnosis.

1. EEG, fundus examination.

2. Skull base film.

3. CT and MRI examinations.

Diagnosis and differentiation of lip and tongue edema and facial paralysis syndrome

Diagnosis is based on swelling of the lips and tongue, facial paralysis, longitudinal fissure of the tongue, etc., and there may be recurrence in the course of the disease.

The disease must be identified with trauma, inflammation and tumors caused by facial paralysis, swelling of the tongue and tongue, skull base film, CT and MRI examinations can be identified.

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