Numismatic palmoplantar keratoderma
Introduction
Introduction to coin-shaped palmoplantar keratosis The keratosis palm keratosis (keratosispalmoplantarisnummularis) is an autosomal dominant genetic disease characterized by hyperkeratotic plaques at the friction site. The pathogenesis is still unclear. Lesions are hyperkeratotic plaques or hypertrophic edulis. It can be used for the treatment of keratin exfoliating agents and vitamin A acid preparations. basic knowledge The proportion of illness: 0.005% Susceptible people: no specific population Mode of infection: non-infectious Complications: diffuse palmoplantar keratosis
Cause
The cause of martial keratosis
(1) Causes of the disease
The cause of this disease is not clear, and it is currently considered to be autosomal dominant. All kinds of races can occur, the incidence of both sexes is roughly equal, and the incidence is statistically high in Northern Ireland at 1:40, with family.
(two) pathogenesis
The pathogenesis is still unclear. Autosomal dominant inheritance. May be autosomal dominant.
Prevention
Coin-like palmoplantar keratosis prevention
The cause of this disease is not clear, and it is currently considered to be autosomal dominant. Therefore, the disease cannot be prevented for the cause. For patients with infectious skin damage, the application of glucocorticoids should be reduced to reduce the possibility of suffering from this disease. Early detection, early diagnosis, and early treatment are important for the prevention of complications, which can effectively reduce the occurrence of complications.
Eat more vegetables, fruits, eat spicy spicy food. Keep your mood comfortable and strengthen your physical exercise. Try to avoid trauma and avoid contact with irritating substances such as soap, alkali and mineral oil.
Complication
Coin-like palmoplantar keratosis complications Complications diffuse palmoplantar keratosis
Protection of the affected area is also a key measure to prevent complications and sequelae. Coin-like palmoplantar keratosis is usually itchy, and there may be obvious pain in the case of serious illness. Avoid the vicious cycle of stimulating the nerve endings, and it is easy to spread and spread, and it is easy to cause comorbidities. (It is easy to cause bacterial infection when the affected area is scratched. It is easy to purulent after the healing of the suppurated wound. scar).
Symptom
Coin-like palm keratosis symptoms common symptoms palmar keratosis excessive palm and plantar keratosis with hyperhidrosis
Most of them have been diagnosed since childhood, and the lesions are excessive keratinized plaque or lenticular hyperkeratosis. The location and severity of skin lesions are related to mechanical friction and its intensity, which are more common in the lateral edge of the palmar sac. Weeks can also be seen excessive keratinization. The crotch is more common and serious than the palm. Conscious pain, severe affecting walking.
Examine
Examination of numismatic palmoplantar keratosis
Clinical skin examination: The skin lesions are excessive keratinized plaque or lenticular hyperkeratosis, which may be accompanied by ulceration, itching of the skin mucosa and yellow transparent liquid exudation. The location and severity of skin lesions are related to mechanical friction and its strength. More common in the palm of the hand. Hyperkeratosis can also be seen under the nails and nails.
Histopathological examination: The main feature is that the focal epidermis is excessively hyperkeratotic, and eosinophils and monocyte infiltration are seen during the period.
Diagnosis
Diagnosis and differentiation of numismatic palmoplantar keratosis
diagnosis
According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.
Differential diagnosis
The disease caters to the identification of athlete's foot and eczema. The latter features thickening, roughening, desquamation and drying of the stratum corneum. The symptoms are mild. Every winter, it is prone to chapped, often in patients with longer disease and longer age. Skin eczema, the appearance is similar to the disease, but eczema usually has obvious itching and keratinized skin peeling, showing light yellow liquid exudation.
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