Kimura reticular acral pigmentation

Introduction

Introduction to Mucheng reticular phlegm pigmentation Muchong reticular phlegm pigmentation (reticularacropymentationofKitamura) is an autosomal dominant hereditary syndrome, rare. The age of onset is 10 to 20 years old. basic knowledge The proportion of illness: 0.001% Susceptible people: between 10 and 20 years old Mode of transmission: mother-to-child transmission Complications: Freckles Multiple leukoplakia

Cause

Kimura reticular pharyngeal pigmentation cause

(1) Causes of the disease

Autosomal dominant inheritance.

(two) pathogenesis

It is possible that the transport of melanosomes to the surrounding keratinocytes is accelerated and the number of active melanocytes is increased, thereby causing hyperpigmentation.

Prevention

Kimura reticular phlegm pigmentation prevention

Avoid sun exposure.

Complication

Kimura reticular acral pigmentation complications Complications Freckle multiple plaque pigmentation

The disease is a chromosomal disease, so there may be other organs and tissue abnormalities, including kidney ectopic, and connective tissue diseases. Secondly, the disease can increase skin pigment residue, so it mainly affects the appearance of the skin. For patients with excessive stress and depression, especially in adolescence, beauty can be affected by skin pigmentation, so it can induce depression, and patients with similar tendencies should pay attention.

Symptom

Muchong reticular phlegm pigmentation symptoms common symptoms freckle pigmentation spots

Damage to the hands, the back of the foot more common, can involve the palmar, neck, can also be seen in the forearm temporal side, calf and other parts of the body surface, the distribution is often wide, eyelids and face can also be involved, the typical characteristics of the disease are: The pigmented spots are freckled, and the temporal part is dense and distinct. The pigmentation is consistent with the direction of the skin, slightly concave compared with the surrounding normal skin, and has an irregular network and an angular shape.

Examine

Kimura reticular phlegm pigmentation examination

Histopathology: The epidermal layer of the pigmented plaque atrophied, the basal layer of melanin increased, and the dermal papillary melanocytes did not increase.

Diagnosis

Diagnosis and identification of reticular phlegm pigmentation in Kimura

According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.

Should be differentiated from hereditary symmetry cutaneous heterochromia.

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