Gastric rhythm syndrome

Introduction to gastric rhythm disorder syndrome Gastric Dysrhythmia syndrome is a group of syndromes in which nausea, vomiting, abdominal pain, and bloating are caused by disordered or too fast gastric motility rhythm. Intrinsic occurs mostly after abdominal surgery, such as cholecystectomy, esophageal hiatal hernia repair or pyloric angioplasty, and extensive damage to severe diabetic autonomic nerves. Other studies have concluded that excitatory neurotransmitters (such as acetylcholine, motilin and gastrin) and inhibitory neurotransmitters (such as norepinephrine, dopamine, vasopressin, enkephalin, etc.) Proportional imbalance can lead to disorders of the stomach rhythm. basic knowledge The proportion of sickness: 0.01% Susceptible people: no specific population Mode of infection: non-infectious Complications: functional dyspepsia gastritis gastroesophageal reflux disease peptic ulcer portal hypertension

Causes of gastric rhythm disorder syndrome

A group of syndromes of nausea, vomiting, abdominal pain, and bloating caused by disordered or too fast gastric motility rhythm. Intrinsic syndrome occurs mostly after abdominal surgery, such as cholecystectomy, hiatal hernia repair or pyloric angioplasty, and severe Diabetic autonomic nerves are extensively impaired, and studies have suggested that fine-proportional imbalances between excitatory neurotransmitters (such as acetylcholine, motilin and gastrin) and inhibitory neurotransmitters (such as norepinephrine, dopamine, etc.) Can cause disorders of the stomach rhythm.

Neurohumoral regulation disorder (30%):

The proportion of gastric excitatory and inhibitory neurotransmitter media is dysregulated. Changes in excitatory and inhibitory stimuli thresholds in gastric smooth muscle cells, and various brain-gut peptides in the central nervous system can determine gastric excitability and inhibition of motor effects. Other humoral factors include gastrin, motilin, serotonin, insulin, and the like.

Disease factors (25%):

Common clinical diseases (1) functional dyspepsia of gastric functional diseases, hyperactivity of gastric vagus nerve, etc. (2) Gastric organic diseases, various gastritis, gastroesophageal reflux disease, peptic ulcer, gastric malignant tumor, postoperative gastrectomy, and vagus nerve resection. (3) systemic diseases small bowel dysmotility, portal hypertension combined with impaired liver function, craniocerebral diseases.

Histopathological changes (28%):

Various diseases cause inflammation of the submucosal plexus and connective tissue hyperplasia, as well as extensive damage to the autonomic nervous system by systemic diseases.

Drug impact (10%):

Morphine, atropine, etc.

Stomach rhythm disorder syndrome prevention

There are no special preventive measures for this disease, and physical exercise should be actively carried out to strengthen its own immunity. This disease is often caused by a combination of factors, and mental and psychological disorders, relationship disorders, bad oral habits, therefore, the key to prevent this disease is to regulate the pace and order of life, reasonable diet, keep the mouth clean, exercise, regular oral examination, It is especially important to treat the abnormal relationship early.

Complications of gastric rhythm disorder syndrome Complications Functional dyspepsia gastritis gastroesophageal reflux disease peptic ulcer portal hypertension

The disease is complicated by the following diseases:

(1) gastric functional diseases

Functional dyspepsia, hyperactivity of the gastric vagus nerve, etc.

(2) gastric organic diseases

Various gastritis, gastroesophageal reflux disease, peptic ulcer, gastric malignant tumor, postoperative gastrectomy, and vagus nerve resection.

(3) systemic diseases

Intestinal dysmotility, portal hypertension, impaired liver function, and brain disease.

Symptoms of gastric rhythm disorder syndrome Common symptoms Small stomach syndrome nausea and vomiting bloating in the upper abdominal pain nausea distal antrum produces ectopic rhythm

Patients may have irregular paced potential (ppesetter potential, pp) or fast rhythm, up to 9 times per minute (normal people 3 to 4 times per minute), even in the distal antrum to produce ectopic rhythm to make pp reverse Propagation of the proximal gastric antrum, and the occurrence of vomiting or retching, female incidence is significantly more than male, clinical manifestations of intermittent nausea, vomiting, upper abdominal pain, early satiety, a small amount of abdominal distension due to gastric retention, gastric myoelectric The figure can record the disorder of gastric myoelectric rhythm, and the diagnosis still needs to exclude organic diseases.

Examination of gastric rhythm disorder syndrome

The electrogastrogram can record the disorder of the gastric electrical rhythm. Gastric emptying measurements have varying degrees of gastric emptying dysfunction, mainly due to delayed emptying.

1, endoscopy: high-tech electronic colonoscopy, from outside the body through the body's natural cavity into the body, to examine the disease in the body, you can directly observe the internal cavity lesions, determine its location, range, and can Photography, biopsy or brushing greatly improve the diagnostic accuracy of cancer and can be used for certain treatments.

2, X-ray examination: X-ray examination of the gastrointestinal tract, showing that the movement of the entire gastrointestinal tract is accelerated, the colonic pocket is deepened, the tension is enhanced, and sometimes the colonic sputum is below the descending colon, and there is no obvious abnormality in the colonic mucosa. .

3. Analysis of gastric juice: The secretion of gastric juice is most affected by food, and the amount of normal fasting gastric juice is about 30-50ml. The amount of gastric juice increased significantly in the absence of eating, suggesting that the amount of gastric secretion is too high and the ability of gastric peristalsis is reduced. For example, when performing gastroscopy on an empty stomach, some patients have a large amount of liquid in the stomach, some are colorless and transparent foam, some are turbid and viscous, and some are yellow-green.

Diagnosis and differentiation of gastric rhythm disorder syndrome

The disease needs to be differentiated from other gastrointestinal organic diseases, such as: gastric ulcer, gastritis, gastric perforation and so on. When gastroscopy reveals a gastric ulcer, the diagnosis seems to be very clear, but attention should also be paid to the identification of digestive tract tumors with a rare specific cause of gastric ulcer or ulceration. The huge ulcer of the stomach has certain difficulties in the identification of gastric malignant tumors on endoscopy, and some ulcers are extremely difficult to distinguish from early cancer. Therefore, if ulcers of the stomach are found during clinical ascending gastroscopy, clinicians usually take alive. The pathological examination was performed, and the patient was asked to review and take a pathological examination of the living tissue after treatment to prevent false negatives.

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