Pneumoniasis

Introduction to pulmonary bud disease Pulmonary bacillosis, also known as Gilchrist disease or North American bud disease, is a chronic granulomatous and suppurative disease caused by Blastomyces Dermatitidis or blastomycosis North American infection. Invade any part of the body, mainly involving the skin, lungs and bones. Pulmonary bacterium is also a biphasic fungus that is found in the soil. basic knowledge The proportion of illness: 0.03%--0.05% Susceptible people: no special people Mode of infection: pathogen infection Complications: empyema

Causes of pulmonary bud disease

Cause:

Inhalation is the main route of infection, so the lungs are usually the primary infection site, which can spread to all organs of the body, mainly invading the skin and bones, and occasionally can be infected through skin contact, causing vaccination blastomycosis, lung lesions Polymorphism, various pathological changes from acute exudative inflammation to chronic proliferative inflammation, the latter is a typical manifestation of this disease.

Pulmonary bud disease prevention

The drug should be selected according to the pathogen species. It should be treated as soon as possible with antifungal drugs. The dermatitis buds have a disease course of 0.5 to 2 years. Serious infections should be combined with synergistic antifungal drugs, such as amphotericin B combined with flucytosine. treatment.

Pulmonary bud disease complications Complications

The pleural mediastinum is often violated.

Pulmonary bud disease symptoms Common symptoms Pleural effusion lymphadenopathy Chest pain growth slow

The disease can be divided into four types: primary pulmonary bacillary bacterium, chronic skin and bone germination, systemic germination and vaccination.

Primary lung bud disease is similar to tuberculosis or histoplasmosis. The symptoms are not specific. Some cases resemble primary tuberculosis. Most of them can heal themselves. A few are subacute or chronic and even spread to the whole body. In patients with T cell dysfunction, the infection is often very serious, difficult to cure, easy to spread to multiple organs and progress rapidly, and the high incidence of extensive lung infiltration and meningeal dissemination is its clinical feature.

1. The disease is endemic fungal disease, and patients often have a history of residence in endemic areas.

2. Laboratory examination: Most cases are diagnosed by smear, culture and histopathology.

(1) Direct microscopic examination: direct microscopic examination of blood, pleural effusion, sputum or other secretions is the simplest and quickest diagnostic method. Under the light microscope, single-spore spores with a double-walled shape of 8-20 m can be seen. The neck is thicker, and histopathological examination of the biopsy specimen is also a good method for establishing a diagnosis, but special staining such as PAS staining, hexamine silver staining, etc. is required.

(2) Culture: It is easy to grow, but the growth is slow, and the conventional culture takes several weeks.

(3) Skin test: mainly used for epidemiological investigation, there is currently no antigen for clinical use.

(4) Serological test: There are methods such as complement fixation test, immunodiffusion method and enzyme immunoassay, which have high specificity and poor sensitivity.

Examination of pulmonary bud disease

Most cases are diagnosed by smear, culture, and histopathology.

1. Direct microscopic examination: direct microscopic examination of blood, pleural effusion, sputum or other secretions is the simplest and quickest diagnostic method. Under the light microscope, single-spore spores with a double-walled shape of 8-20 m can be seen. Thicker, histopathological examination of biopsy specimens is also a good method to establish a diagnosis, but special staining such as PAS staining, hexamine silver staining, etc. is needed.

2. Bacterial culture: It is easy to grow, but the growth is slow, and the conventional culture takes several weeks.

3. Skin test: mainly used for epidemiological investigation, there is currently no antigen for clinical use.

4. Serological test: There are complement fixation test, immunodiffusion method and enzyme immunoassay, etc., which have high specificity and poor sensitivity.

X-ray chest radiographs may have lung lesions and/or hilars, mediastinal lymph nodes.

Diagnosis and identification of pulmonary bud disease

Pay attention to the identification of diseases such as tuberculosis, histoplasmosis, sarcoidosis, actinomycosis, and nocardiosis.

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