Generalized idiopathic telangiectasia

Introduction

Introduction to generalized idiopathic telangiectasia Generalized essential telangiectasia refers to diseases in which the limbs, large venules of the trunk and telangiectasia are not associated with other skin lesions, and are more common in women. basic knowledge The proportion of illness: 0.004%-0.008% Susceptible people: more than 40 to 50 years old women Mode of infection: non-infectious Complications: fever

Cause

Generalized idiopathic telangiectasia

(1) Causes of the disease

The cause is not clear.

(two) pathogenesis

It was reported that one case was cured by oral administration of tetracycline, and the other case disappeared after the sinus infection was cured, suggesting that bacterial toxin may cause the disease. The authors also found that the expanded vascular endothelial cells lack alkaline phosphatase.

Prevention

Generalized idiopathic telangiectasia prevention

1. Strengthen care and nutrition: to improve the patient's resistance and immunity.

2. Prevention of infection: attention should be paid to isolation to minimize contact with pathogens.

Complication

Generalized idiopathic telangiectasia complications Complications

Generalized idiopathic telangiectasia mainly refers to people with certain skin diseases (such as rosacea, etc.), and some people have unclear reasons. With this skin disease, the face is very prone to redness, and the color will not only deepen when it is hot, emotional, strenuous, or drinking.

Symptom

Generalized idiopathic telangiectasia symptoms Common symptoms telangiectasia redness on the cheeks

Occurred in women 40 to 50 years old, the damage is extensive linear telangiectasia, the initial damage is located in the calf, and then spread to the thigh, abdomen, buttocks and upper limbs, the lesion can be generalized, unilateral or Limited to a large area of the lower limbs, upper limbs, trunk or cutaneous nerve walking area, scattered or fused together, can also be expressed as small hemangioma, some patients with conjunctiva and oral mucosa can also be affected, but no systemic lesions And bleeding.

Examine

Generalized idiopathic telangiectasia

Histopathology: telangiectasia, hyperemia, and wall defects in the dermis, consisting only of endothelial cells, negative for histochemical staining showing alkaline phosphatase activity of the vascular iliac artery, indicating that the expanded capillaries are capillary vasospasm The vein part.

Diagnosis

Diagnosis and differentiation of generalized idiopathic telangiectasia

According to the occurrence of limbs, the trunk veins and telangiectasia, extensive distribution without other damage can be diagnosed.

Differential diagnosis

1. Atypical hereditary hemorrhagic telangiectasia: The lesion is prone to occur in the upper part of the body, widely distributed, symmetrical, and has a tendency to bleed.

2. Capillary expansion with systemic disease: There are various systemic primary disease manifestations. Histochemical staining shows that active alkaline phosphatase is present in endothelial cells at the distal arterioles and capillaries, but the intrinsic no .

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