Hemorrhagic cystitis

Introduction to hemorrhagic cystitis Hemorrhagic cystitis refers to the acute or chronic damage to the bladder caused by certain drugs or chemicals in the urine, resulting in extensive inflammatory bleeding in the bladder. The disease is a complication of multiple causes, which is common in the treatment of cancer patients, mostly due to the toxicity or allergic reaction of anti-tumor drugs, radiation damage caused by high-potential pelvic irradiation, and also in some viral infections, such as Adenovirus, influenza virus infection, etc. basic knowledge The proportion of sickness: 0.002% - 0.008% Susceptible people: no specific people Mode of infection: non-infectious Complications: anemia shock

Causes of hemorrhagic cystitis

(1) Causes of the disease

There are many substances that cause bladder bleeding, such as alkylating agents, busulfan, thiotepa, aniline, toluidine derivatives, insecticides, etc., and also in some viral infections, such as adenovirus, influenza virus infection.

(two) pathogenesis

The bladder is the last organ that stores and excretes many drugs or chemicals in the urine. These high concentrations of urine are in contact for a long time, causing acute or chronic damage to the bladder mucosa, causing chemical inflammation, causing extensive bleeding of the bladder, such as cyclophosphorus. The amide itself has no effect on the bladder, but its metabolites can cause hemorrhagic cystitis.

Hemorrhagic cystitis prevention

Hemorrhagic cystitis refers to the acute or chronic damage to the bladder caused by certain drugs or chemicals in the urine, leading to extensive inflammatory hemorrhage of the bladder. Therefore, prevention should focus on avoiding excessive intake of the above drugs. Also seen in certain viral infections, such as adenovirus, influenza virus infection, etc., the above-mentioned pathogen infection needs to be actively treated to avoid the induction of hemorrhagic cystitis. There is no effective preventive measure for this disease. Early detection and early diagnosis is the prevention and treatment of this disease. The essential.

Hemorrhagic cystitis complications Complications anemia shock

1. Anemia: Patients with this disease can see continuous gross hematuria, which can lead to hemorrhagic anemia due to chronic persistent loss of red blood cells.

2. Shock: For severe cases of this disease, a large amount of blood can be lost in a short time, resulting in a decrease in blood volume, resulting in a low-volume shock.

3. Sepsis: For patients with cystitis infection and low resistance, long-term use of immunosuppressive drugs, sepsis can be caused by infection of pathogens into the blood.

Hemorrhagic bladder inflammation symptoms Common symptoms Hematuria and tibia dysplasia

1. Hematuria and hematuria can be light and heavy, and lighter only has microscopic hematuria. Severe can cause anemia and hemodynamic changes in hemorrhage. It can be sudden massive hematuria or intractable hematuria.

2. The medical history often has post-tumor radiotherapy, chemotherapy and other drugs, and the history of toxic exposure.

Hemorrhagic cystitis check

Urine routine examination may have microscopic or gross hematuria; blood anemia is routinely checked for hemoglobin reduction.

B-ultrasound, cystoscopy: exclusion of space-occupying lesions, mucosal congestion and edema, ulcer necrosis.

Diagnosis and diagnosis of hemorrhagic cystitis

For those with alkylating agents, busulfan, aniline, toluidine derivatives, pesticide contact history, clinical appearance of hematuria, the possibility of this disease should be considered, combined with cystoscopy, B-ultrasound, and more A diagnosis can be made.

1. Bladder tumors also manifest as gross hematuria, but patients usually have painless hematuria, and B-ultra and cystoscopy can be seen in the bladder, rather than extensive bleeding in the bladder mucosa.

2. Acute cystitis can also be manifested as gross hematuria, but often with frequent urination, urgency, and a large number of white blood cells in the urine. There is no history of exposure to certain drugs or chemicals, and hematuria can be quickly disappeared by antibiotics.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.