Persistent erythema raised

Introduction to persistent inflammatory erythema Persistence erythema (erythemaelevatumdiutinum) is a rare skin disease characterized by persistent red, purple and yellow papules, plaques and nodules that are often symmetrically distributed. The occurrence of this disease is mostly caused by blood and heat, cold, and dampness. basic knowledge The proportion of the disease: the incidence rate is about 0.001% -0.002% Susceptible people: mostly in adults Mode of infection: non-infectious Complications: pruritic urticaria and plaque in pregnancy

Persistent inflammatory erythema

(1) Causes of the disease

It may be due to a bacterial infection or an immune response to the skin's blood vessels, which is often accompanied by rheumatism. It has also been reported to be caused by penicillin and sulfa drugs.

(two) pathogenesis

The cause is unclear and the pathogenesis is unknown. It may be an immune response of the bacterial infection or its toxin to the blood vessels of the skin. It is also reported that the drug causes the disease.

Persistent inflammatory erythema prevention

Finding the cause, early targeted treatment of primary disease, early diagnosis, early treatment is the key to prevent this disease.

Persistent inflammatory erythema complications Complications Pregnancy pruritic urticaria papules and plaque

The disease often has itchy skin and ulcers. After the ulcer occurs, it can leave scar tissue, residual pigmentation and atrophy. Therefore, patients with skin ulcers should be treated actively to promote the healing of ulcers. The common cause is due to local skin and bacterial infections, usually secondary to low body weight, or long-term use of immunosuppressants, pay attention to maintain The skin is clean, and if the skin is superficial, the iodophor disinfection can reduce the occurrence of complications.

Persistent inflammatory erythema symptoms common symptoms rash pruritus nodules

Adults, with recurrent polyarthritis, persistent brown-colored maculopapular rashes, nodules and plaques, often beginning with pale red broad beans, soft nodules, gradually developing into lavender or brown The red is irregular, the shape is solid and plaque, or it is large. The surface of the skin lesion is smooth and the boundary is clear. Some of them can be similar to the yellow tumor. The skin lesions often appear purple, and the skin lesions are mainly distributed on the extremities of the extremities. With the back of the hands and feet and the elbow and knees extending more, the pathologically slow skin lesions can last for several months to several years, sometimes they can subside themselves, leaving pigmentation and atrophy, and the scars appear after the ulcers appear.

1. It occurs mostly in adults, but also affects children and young people. Both men and women have no obvious systemic symptoms, and may also be associated with recurrent polyarthritis.

2. Skin lesions are persistent brown-red maculopapular rashes, nodules and plaques. They are often pale red broad beans at the beginning, softer nodules, gradually developed into lavender or brown-red irregularities, and solid plaques , or into a large piece, the surface of the skin lesion is smooth, the boundary is clear, and some can be similar to xanthomas, purpura often appears on the skin lesions, a few lesions appear blisters or bullae, occasionally ulcers, damage with mild itching and pain, Tenderness and burning sensation.

3. Skin lesions are mainly distributed in the extremities of the extremities, especially in the back of the hands and feet and the extension of the elbow and knee. A few of them involve the palm, ankle, hip and ear, and have multiple symmetry distributions, which rarely invade the mucosa.

4. The course of the disease is slow: the skin lesions can last for several months to several years, sometimes they can subside on their own, leaving pigmentation and atrophy. The ulcers will leave scars, and some new rashes will continue to prolong.

Persistent inflammatory erythema examination

Histopathology, typical leukocyte fragment vasculitis, early dermal wall and deep vascular plexus vascular wall and perivascular dense neutrophil-based infiltration, tube wall swelling, red staining, a large amount of fiber Substance deposition, neutrophils around the tube, nuclear dust and a few extracellular red blood cells, mixed with lymphocytes and a few eosinophils, old lesions with fibroblasts and capillary proliferation, and lipid deposition.

Persistent inflammatory erythema diagnosis

Clinically, it needs to be differentiated from annular granuloma, xanthoma, and sarcoidosis, and histologically should be differentiated from facial granuloma and Sweet disease.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.