Cholera-like syndrome

Introduction to cholera-like syndrome The bonfire-like (Janbon) syndrome refers to the acute necrotizing inflammation of the colon or / and small intestinal mucosa covered with pseudomembrane composed of cellulose, mucus, necrotic mucosa and inflammatory cells, hence the name pseudomembranous. Enteritis, post-operative enteritis, antibiotic-associated enteritis, anal-rectal syndrome. It is believed that the intrinsic infection is caused by Clostridium difficile. Intrinsic diarrhea, mostly watery diarrhea, mucus. basic knowledge Sickness ratio: 0.0001% Susceptible people: no specific population Mode of infection: non-infectious Complications: paralytic ileus

Causes of cholera-like syndrome

It is thought that the intrinsic infection is caused by Clostridium difficile. In some seriously ill patients, trauma, surgery, stress and taking broad-spectrum antibiotics can induce the intrinsic, and the exotoxin produced by Clostridium difficile can make Small blood vessels coagulate, thrombosis, intestinal wall necrosis or even perforation; and toxins stimulate the cAMP system in mucosal epithelial cells, causing cholera-like symptoms.

Cholera-like syndrome prevention

Active prevention of infection after surgery is a good measure to prevent this disease.

Complications of cholera-like syndrome Complications paralytic ileus

Toxic megacolon, paralytic ileus, intestinal perforation.

Symptoms of cholera-like syndrome Common symptoms Diarrhea, abdominal pain, dehydration, nausea, watery diarrhea, hypokalemia, edema, shock

Intrinsic diarrhea, mostly watery diarrhea, mucus, severe defecation can reach 4000ml per day, some patients discharge characteristic pseudomembrane, diarrhea has nothing to do with the dose and duration, may have abdominal pain, nausea, vomiting, etc. Gastrointestinal symptoms, and often have fever, tachycardia, and even dehydration, shock, acidosis, sputum and other symptoms of toxemia.

Examination of cholera-like syndrome

1. Laboratory examination: peripheral leukocytosis, mainly neutrophils.

2. Endoscopy: timely endoscopic examination can not only confirm the diagnosis at an early stage, but also understand the extent and extent of the lesion. In the light, mucosal congestion and edema can be seen, and the vascular texture is unclear. Slightly heavy, the mucous membranes are scattered in superficial erosion, pseudo-membrane-like distribution, peripheral congestion, and severe pseudoplaques or maps.

3. X-ray examination: abdominal plain film, barium enema examination.

Diagnosis and identification of cholera-like syndrome

diagnosis

Under colonoscopy, the intestinal mucosa is congested, edema, increased fragility, ulcer bleeding and yellow-white, gray-green patchy pseudomembrane, and culture of Clostridium difficile is often positive.

Differential diagnosis

Need to be differentiated from acute necrotic enteritis, inflammatory bowel disease, ischemic bowel disease and cholera.

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