Benign lipoblastoma

Introduction to benign lipoblastoma Benignlipoblastoma is a rare isolated tumor, mostly occurring in infants, 80% of which occur before the age of 3, so it is also called embryonal lipoma (embryonallipoma), which is similar to fetal adipose tissue. Localized (fat cell tumor) or diffuse (fatoma) tumor. Tumors are most common before the age of 3. Occasionally occurs in newly born or older children, and the incidence is male. The extremities are the most frequently involved sites, as well as reports of mediastinal, retroperitoneal, trunk, head and neck, and various organs (lung, heart, parotid gland). basic knowledge The proportion of illness: 0.003% Susceptible people: no special people Mode of infection: non-infectious Complications: headache

The cause of benign lipoblastoma

(1) Causes of the disease

The cause is still unknown, and may be related to genetics. Fatty blastoma has a simple pseudo-diploid karyotype with chromosomal aberrations. It has also been reported that chromosomal rearrangement in lipoblastoma can lead to two different fusion genes.

(two) pathogenesis

The pathogenesis is still unclear.

Benign fat cell tumor prevention

The precautionary principle is early detection and early treatment. You should first focus on and improve those factors that are closely related to our lives, such as quitting smoking, eating properly, exercising regularly, and losing weight. Appropriate exercise, enhance physical fitness and improve your disease resistance. Anyone who follows these simple and reasonable lifestyles can reduce their chances of developing benign lipoma.

Benign fat cell tumor complications Complications

Hemangioblastoma is a benign tumor of high vascular differentiation produced by the cranial and spinal nerves. Most hemangioblastomas are produced by a single lesion. However, in a patient with the so-called "vonHippelLindau" (VHL) disease, hemangioblastoma is a manifestation of this genetic syndrome.
Can be complicated by retinal hemangioma, splanchnic cyst or hemangioma, polycythemia. As hemangioblastoma grows, an increasing number of tumors will compress into the brain and cause some neurological symptoms such as headache, limb weakness, loss of sensation, balance and coordination problems, or hydrocephalus.

Benign fatty blastoma symptoms common symptoms slow growth

Occurs in the lower extremities, mostly confined to the skin, is spherical or lobulated, slowly growing, the lesion is relatively small, the diameter is often 3 ~ 5cm, the tumor has a fat-like appearance, a local gel-like area, soft texture Most of the lesions have a slowly increasing soft tissue mass, and the boundary is clear. The deep boundary is unclear. According to the location, the tumor can compress nearby tissues, such as the trachea. The imaging examination shows that the tumor has the same density as the adipose tissue and cannot be associated with lipoma. It is different from liposarcoma.

Examination of benign lipoblastoma

Histopathology: Fatty blastoma has a lobulated appearance, mixed with mature and immature fat cells, the tumor location can be superficial, can also reach deep into muscle tissue, composed of immature embryonic adipocytes and mucinous interstitial, fat Mother cells vary in size and shape. They contain single or several vacuoles of different sizes. The vacuoles are smaller than mature adipocytes, forcing the nucleus to cling to the capsule, mucinous interstitial plexiform capillaries and fine Intravenously rich, containing non-cavitating fusiform or star-shaped naive mesenchymal cells.

Diagnosis and differentiation of benign lipoblastoma

Mucin-like liposarcoma is seen in atypical fatty cells, mitotic figures and deep nuclear staining, which are rare in infants and young children.

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