Enteropathogenic Escherichia coli infection

Introduction to enteropathogenic Escherichia coli infection Enteric infectious disease caused by enteropathogenic Escherichiacoli (EPEC). EPEC is a group of diarrhea-causing Escherichia coli that was recognized as early as the 1940s. It was the main pathogen of epidemic diarrhea in infants from the 1950s to the 1960s. It is called "dyspepsia" clinically. In 1983, the national diarrhea experience exchange symposium decided that the diarrhea caused by EPEC would be called EPEC enteritis, not called "dyspepsia". basic knowledge Sickness ratio: 0.5% Susceptible people: no specific people Mode of infection: pathogen infection Complications: Isotonic dehydration Metabolic acidosis Hypokalemia Pneumonia

Enteropathogenic Escherichia coli infection etiology

(1) Causes of the disease

The form of EPEC is the same as that of common Escherichia coli. The identification of the two depends mainly on the serotype. EPEC has 13 common serotypes, with the largest number of 0111, accounting for 40% to 50% of the total number of cases.

(two) pathogenesis

The positive pathogenicity of EPEC is that they have the ability to adhere to the surface of the intestine. The pathogen enters the small intestine by mouth, grows in the upper part of the duodenum, jejunum and ileum, adheres to the surface of intestinal epithelial cells, or is embedded on the surface of intestinal epithelial cells. In the depression, the mucosa is characterized by characteristic damage, local microvilli atrophy, intestinal dysfunction, and even intestinal mucosal necrosis, ulceration, and diarrhea. In addition, EPEC can produce African green monkey cytotoxin (VT), causing intestinal epithelial cells. The secretion of fluid into the intestinal lumen, non-specific congestion, edema, heart, liver, kidney, central nervous system are more obvious.

Enteropathogenic Escherichia coli infection prevention

Do a good source of infection management and digestive tract isolation.

Enteropathogenic Escherichia coli infection complications Complications isotonic dehydration metabolic acidosis hypokalemia pneumonia

There are severe isotonic dehydration, metabolic acidosis, low potassium, low calcium, pneumonia, heart, liver, kidney dysfunction, sepsis and so on.

Intestinal pathogenic Escherichia coli infection symptoms Common symptoms Intestinal palsy, lack of appetite, diarrhea, dysentery, diarrhea, bloating

1. The incubation period is generally 2 to 5 days.

2. Symptoms and signs usually slower onset, but also acute onset, irregular diet, improper feeding and other incentives, mild fever, the main symptoms are diarrhea, 3 to 5 times a day, a yellow egg pattern band Milk flaps, a large amount, the disease continues to develop, there is fever, vomiting, loss of appetite, abdominal distension, toxic intestinal paralysis, diarrhea before the emergence of intestinal paralysis, mucus and bloody stools, adult patients often acute onset, umbilical pain, Abdominal snoring, occasionally heavy and heavy, showing "dysentery."

Examination of intestinal pathogenic Escherichia coli infection

The surrounding blood is normal or the white blood cells are slightly higher. A small amount of red and white blood cells can be seen in the stool examination, and there are a lot of fat spheres.

Diagnosis and identification of enteropathogenic Escherichia coli infection

According to the fecal culture of Escherichia coli positive and serotype positive can not be diagnosed, must have clinical manifestations and epidemiological support to diagnose the disease.

The diseases that need to be identified with them are dysentery, salmonella enteritis, Campylobacter jejuni enteritis, viral enteritis and children with acute rash.

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