Progressive bulbar palsy

Introduction

Introduction to progressive bulbar palsy Progressive medullary (ball) paralysis is a degenerative disease of the nucleus of the medullary and cerebral cranial nerves. It is a type of motor neuron disease with progressive dysphagia, unclear articulation, and weakness of the facial and masticatory muscles. It is a progressive medullary paralysis. Among them, amyotrophic lateral sclerosis has a rapid onset and serious illness, which can cause paralysis and even life-threatening. Progressive medullary paralysis can cause difficulty in breathing, vomiting, and unclear pronunciation, which seriously affects the quality of life of patients, and is often life-threatening due to concurrent aspiration pneumonia and asphyxia. The lesion mainly invades the medulla and pons motor nucleus. The disease usually begins after the age of 40, with more men than women. After the disease, the average survival time is 2 to 3 years. Faster progress, poor prognosis, and more than 1 to 3 years of death from respiratory muscle paralysis and lung infection. basic knowledge The proportion of illness: 0.002% - 0.005% Susceptible people: no specific population Mode of infection: non-infectious Complications: malnutrition pneumonia

Cause

Progressive medullary palsy

It is a group of chronic progressive degenerative diseases in which the anterior horn cells of the spinal cord, the motor brain of the brainstem group, the cortical pyramidal cells and the pyramidal tract are unclear, and the clinical features are the symptoms of upper and lower motor neurons. Signs of coexistence, manifested as muscle weakness, muscle atrophy and pyramidal tract signs of different combinations, sensory and sphincter function is generally unaffected.

Prevention

Progressive medullary palsy prevention

Complication

Progressive medullary palsy complications Complications

Symptom

Progressive medullary paralysis symptoms common symptoms pharyngeal reflex sound hoarse tongue muscle atrophy reflex arc interruption forceless cough

Often starting after the age of 40, more men than women. The earliest symptoms were difficulty in articulation, and the speech was slightly unclear. Gradually, there are nasal sounds, hoarseness, chewing weakness, difficulty swallowing, and easy coughing when eating. Saliva often flows from the lips that cannot be closed. Poor cough, throat and tracheal secretions unable to cough up. At the most severe, the muscles of the tongue, soft palate, throat, vocal cords, lips, and face are paralyzed. The nervous system examination shows that the tongue muscle, the facial muscles, the masticatory muscles are weak and atrophy, and the muscle bundles are vibrated, especially the tongue muscles are more obvious. The bilateral soft palate could not be lifted, and the soft palate reflex and the pharyngeal wall reflex disappeared. The throat and face feel are barrier-free.

Examine

Progressive medullary examination

Auxiliary inspection:

1. Skull X-ray examination without fracture found.

2. There was no obvious abnormal change in the cranial and intracranial CT scan of the brain.

3. EEG examination for several months after injury

Diagnosis

Progressive diagnosis of progressive medullary paralysis

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