Latent syphilis

Introduction to latent syphilis Syphilis is a chronic systemic sexually transmitted disease caused by infection with Treponema pallidum, which is mainly transmitted through sexual intercourse. The disease is extremely complex and can almost invade all organs of the body, causing damage to multiple organs. Such as the first stage syphilis infection ulcer or hard sputum; secondary syphilis skin mucosal damage and lymphadenopathy; third syphilis heart, nerves, stomach, eyes, ear involvement and gum damage, etc., syphilis can also be transmitted through the placenta The next generation, causing neonatal congenital syphilis, is extremely harmful. Because syphilis is a serious hazard to human health, it is one of the eight key prevention and treatment diseases prescribed by the Ministry of Health of China. basic knowledge The proportion of illness: 0.02% - 0.05% Susceptible people: no specific population Mode of transmission: sexual transmission Complications: secondary syphilis, third-stage syphilis, syphilis

Latent syphilis

Syphilis is a chronic disease. Although there is a large amount of Treponema pallidum in the initial damage, syphilis is not a simple inflammatory reaction caused by the release of toxic or inflammatory substances or syphilis spirochetes present in tissues. In the acute inflammatory response, monocytes dominate, and multinucleated white blood cells occupy this position. In the early stage of syphilis infection, there are a large number of syphilis spirochetes outside the cells close to the blood vessels.

Latent syphilis prevention

As with other infectious diseases, we should first strengthen health publicity and education, oppose unfair sexual behavior, and secondly take the following preventive measures.

(1) All suspected patients should be examined and tested for syphilis serum in order to detect new patients early and treat them promptly;

(2) Patients with syphilis must be forced to undergo isolation treatment. The patient's clothing and supplies, such as towels, clothes, razors, tableware, bedding, etc., should be strictly disinfected under the guidance of medical personnel to eliminate the source of infection;

(3) Tracking the patient's sexual partners, including patient self-reports and medical personnel visits, finding all sexual contact persons, conducting preventive examinations, tracking observations and performing necessary treatments. The spouse is absolutely forbidden to have sex before the cure;

(4) For pregnant women with suspected syphilis, preventive treatment should be given in time to prevent the infection of syphilis to the fetus; unmarried men and women patients can not get married without being cured.

Latent syphilis complications Complications, secondary syphilis, syphilis, syphilis

When the body is in poor health at a certain stage and the immune function is lowered, Treponema pallidum can take advantage of the opportunity to extensively act in the human body and damage various tissues.

Latent syphilis symptoms common symptoms syphilis infection mucosal rash

Latent syphilis refers to patients who have been diagnosed with syphilis. In a certain period of time, no abnormal findings were found on skin, mucous membranes, and any organ system and cerebrospinal fluid examination. Physical examination, chest X-ray lacks clinical manifestations of syphilis, cerebrospinal fluid examination is normal, and only syphilis Those who are seropositive, or have a clear history of syphilis infection, have never had any clinical manifestations, called latent syphilis.

The diagnosis of latent syphilis is based on the history of the first-stage, second-stage syphilis, the history of contact with syphilis, and the history of babies who have given birth to congenital syphilis. Previous syphilis serum test negative results and disease history or exposure history help In determining the duration of latent syphilis, the infection time is less than 2 years of latent syphilis, more than 2 years is late late syphilis, and the other is latent syphilis with unclear disease period. The latent syphilis does not show symptoms because of the body's own immunity. Strong, or due to treatment, the spirochete is temporarily inhibited. During the latent syphilis, the Treponema pallidum still appears intermittently in the blood. Pregnant women with latent syphilis can infect the fetus in the uterus, and can also be infected with blood donors due to blood donation.

Latent syphilis check

Early latent syphilis can be judged based on the following conditions:

1 continuous syphilis serological test changes, that is, whether the non-helical test increased by 4 times or more;

2 whether there is a history of symptoms of primary or secondary syphilis;

3 Whether the sexual partner has a disease, the second phase or the latent syphilis within 2 years;

4 gene detection of Treponema pallidum DNA positive can be diagnosed, except for early latent syphilis, almost all of the syphilis of unknown age, this type of syphilis should be treated according to late latent syphilis, latent syphilis diagnosed after neonatal period, The mother's medical history and the birth of the child should be carefully analyzed to determine whether the patient is congenital or acquired syphilis. All patients with latent syphilis should be examined for signs of syphilis, such as aortitis, neurosyphilis, gums and iritis. .

Latent syphilis diagnosis and identification

1 genital herpes: the beginning of the micro-convex erythema, 1, 2 days after the formation of clustered small herpes zoster, self-conscious itching, not hard, can be resolved after 1-2 weeks, but easy to relapse. Tissue culture was herpes simplex virus and Tzank smear was positive. PCR detected herpes virus DNA as positive.

2 sputum-like pyoderma: the pathogen is Staphylococcus aureus or Streptococcus. The shape of the lesion was similar to that of the hard chancre, but there was no typical cartilage-like hardness, no dark red infiltration around it, no history of unclean sexual intercourse, and negative syphilis. The nearby lymph nodes can be swollen, but the skin lesions will subside.

3 soft squat: also one of sexually transmitted diseases, a history of sexual contact, caused by Duery Haemophilus. The incubation period is short (3-4 days), the onset is acute, the inflammation is remarkable, the pain is soft, the skin lesions are often multiple, the surface has purulent secretions, and Haemophilus ducrei can be detected, and the syphilis serum test is negative.

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