Retinal Pigment Epitheliitis
Introduction
Introduction to retinal pigment epitheliitis Retinal pigment epithelial inflammation is also known as Krill's disease. The characteristic manifestation is acute acute and severe vision loss in healthy young adults, and the pigmentation epithelium in the macular area can be seen in fundus examination. The incidence of men and women is comparable, and it can be unilateral and bilateral. A fundus examination revealed a small black spotted lesion in the macula, surrounding a small halo ring. Acute onset and self-limiting course of disease may be caused by a viral infection. The cause is unknown. It may be that the pigment epithelium is also infected with some systemic diseases due to viral infection. The prevention of this disease is mainly the ban on hormones. It has been reported that hormone therapy can cause an increase in recurrence rate and worsening of the condition of most patients. It is very important to maintain a good attitude, to maintain a good mood, to have an optimistic, open-minded spirit, and to be confident in the fight against disease. Don't be afraid, only in this way can you mobilize your subjective initiative and improve your body's immune function. basic knowledge The proportion of illness: 0.002% Susceptible people: no specific population Mode of infection: non-infectious Complications: retinal detachment
Cause
Causes of retinal pigment epitheliitis
Cause:
The cause is unknown. It may be that the pigment epithelium is also infected with some systemic diseases due to viral infection.
Prevention
Retinal pigment epithelial prophylaxis
With the ban on hormones, it has been reported that hormone therapy can cause an increase in recurrence rates and worsening of the condition in most patients. It is very important to maintain a good attitude, to maintain a good mood, to have an optimistic, open-minded spirit, and to be confident in the fight against disease. Don't be afraid, only in this way can you mobilize your subjective initiative and improve your body's immune function.
Complication
Retinal pigment epitheliitis complications Complications
In some cases, shallow retinal serous detachment is seen in the macula.
Symptom
Symptoms of retinal pigment epithelium common symptoms visual impairment
1. Conscious symptoms: The onset is acute, the visual acuity drops sharply, the visual acuity is gray, and there is a small vision, but after vision, the visual acuity can return to normal, and the visual field examination has a relative central dark spot.
2, fundus performance: the posterior pole visible lesion cluster, round about 1/4PD size, gray-black small dots into a grape string, sometimes combined with retinal neuroepithelial serous flat detachment, surrounded by pigmentation yellow White ring, after the disease can be left with little spots or no traces, to the retreat period, the gray point becomes black or light color and can not be seen clearly, the light color ring disappears.
3, fundus fluorescein angiography: clusters of grape-like fluorescent spots visible in the macula, and ring-shaped foci in the middle black (covering fluorescence) bright (transparent fluorescence), sometimes a small amount of fluorescein leakage.
Examine
Examination of retinal pigment epitheliitis
1. Fundus fluorescein angiography: the grape-like fluorescent spots of the family in the macula, and the ring-shaped foci of the black (covering fluorescence) and bright (transparent fluorescence), sometimes with a small amount of fluorescein leakage.
2. Optical coherence tomography (OCT): OCT in the acute phase shows thickening of the macular area, and accumulation of heterogeneous material in the outer layer of photoreceptors can be found under the outer membrane and IS/OS line. RPE cells may have irregular fractures, no retinal cysts and subretinal fluid. As the disease subsided, IS/OS recovered completely, and the non-shaped substances gradually absorbed.
Diagnosis
Diagnosis and differentiation of retinal pigment epitheliitis
diagnosis
1, more common in young adults, acute onset, more than one eye suddenly onset, or both eyes have a history of disease, there is a tendency to self-limiting, repeated recurrence can cause permanent visual impairment.
2, visual acuity is rapidly reduced, the shadow in front of the eyes, the visual distortion of the object.
3, the typical signs of the fundus are yellow spots visible dark gray spots around the light pigment ring, multi-family integrated grape-like, fluorescent contrast can be seen in the black and bright fluorescent phenomenon.
Differential diagnosis
1. Central serous chorioretinopathy.
2. Retinal pigment epithelial detachment.
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